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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 361 - 365 (5page)
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초록· 키워드
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Epilepsy has been known to humankind since antiquity. The surgical treatment of epilepsy began in the early days of neurosurgery and has developed greatly. Many surgical procedures have stood the test of time. However, clinicians treating epilepsy patients are now witnessing a huge tide of change. In 2017, the classification system for seizure and epilepsy types was revised nearly 36 years after the previous scheme was released. The actual difference between these systems may not be large, but there have been many conceptual changes, and clinicians must bid farewell to old terminology. Paradigms in drug discovery are changing, and novel anti-seizure drugs have been introduced for clinical use. In particular, drugs that target genetic changes harbor greater therapeutic potential than previous screening-based compounds. The concept of focal epilepsy has been challenged, and now epilepsy is regarded as a network disorder. With this novel concept, stereotactic electroencephalography (SEEG) is becoming increasingly popular for the evaluation of dysfunctioning neuronal networks. Minimally invasive ablative therapies using SEEG electrodes and neuromodulatory therapies such as deep brain stimulation and vagus nerve stimulation are widely applied to remedy dysfunctional epilepsy networks. The use of responsive neurostimulation is currently off-label in children with intractable epilepsy.
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등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Catenoix H / 2018 / The combination of stereo-EEG and radiofrequency ablation / Epilepsy Res 142:117~120
Cobourn K / 2018 / Early outcomes of stereoelectroencephalography followed by MR-guided laser interstitial thermal therapy: a paradigm for minimally invasive epilepsy surgery / Neurosurg Focus 45:E8
Engel J Jr / 1998 / Classifications of the International League Against Epilepsy:time for reappraisal / Epilepsia 39:1014~1017
Feindel W / 2009 / Epilepsy surgery: historical highlights 1909-2009 / Epilepsia 50(Suppl 3):131~151
Fisher RS / 2017 / Operational classification of seizure types by the International League Against Epilepsy: position paper of the ILAE Commission for classification and terminology / Epilepsia 58:522~530
Cobourn K / 2018 / Early outcomes of stereoelectroencephalography followed by MR-guided laser interstitial thermal therapy: a paradigm for minimally invasive epilepsy surgery / Neurosurg Focus 45:E8
Engel J Jr / 1998 / Classifications of the International League Against Epilepsy:time for reappraisal / Epilepsia 39:1014~1017
Feindel W / 2009 / Epilepsy surgery: historical highlights 1909-2009 / Epilepsia 50(Suppl 3):131~151
Fisher RS / 2017 / Operational classification of seizure types by the International League Against Epilepsy: position paper of the ILAE Commission for classification and terminology / Epilepsia 58:522~530
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