메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Lee, Jong-Ki (Department of Food Science and Technology, Youngnam University) Cho, Jin-Gyeong (Graduate School of Biotechnology and Institute of Life Science & Resources, Kyung Hee University) Song, Myoung-Chong (Graduate School of Biotechnology and Institute of Life Science & Resources, Kyung Hee University) Yoo, Jong-Su (Graduate School of Biotechnology and Institute of Life Science & Resources, Kyung Hee University) Lee, Dae-Young (Graduate School of Biotechnology and Institute of Life Science & Resources, Kyung Hee University) Yang, Hye-Joung (Graduate School of Biotechnology and Institute of Life Science & Resources, Kyung Hee University) Han, Kyung-Min (Graduate School of Biotechnology and Institute of Life Science & Resources, Kyung Hee University) Kim, Dong-Hyun (Graduate School of Biotechnology and Institute of Life Science & Resources, Kyung Hee University) Oh, Young-Jun (Graduate School of Biotechnology and Institute of Life Science & Resources, Kyung Hee University) Jeong, Tae-Sook (National Research Laboratory of Lipid Metabolism & Atherosclerosis, Korea Research Institute of Bioscience and Biotechnology) Baek, Nam-In (Graduate School)
저널정보
한국응용생명화학회 Applied Biological Chemistry Applied Biological Chemistry 제52권 제6호
발행연도
2009.1
수록면
646 - 654 (9page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
The dried and powdered tubers of Corydalis turtschaninovii (C. turtschaninovii) were extracted with 80% aqueous MeOH, and the concentrated extracts were partitioned using the acidity and polarity of the solvents. From the alkaloid fraction, nine alkaloids were isolated through repeated $SiO_2$ column chromatography. Based on NMR, MS and IR spectroscopic data, the chemical structures of the compounds were determined to be (${\pm}$)-demethylcorydalmine (1), (+)-isocorydine (2), (+)-stylopine (3), (-)-${\alpha}$-N-methylcanadine (4), pseudoprotopine (5), tetrahydroprotopapaverine (6), allocryptopine (7), berberine (8), and pseudocoptisine (9). This was the first report in which compounds 1, 2, 4, 6, and 7 were isolated from the tuber of C. turtschaninovii. And because the NMR data for some compounds have been incorrectly or incompletely identified in previous literature, they were revised on the basis of 2D NMR experiments. Compounds 1, 2, and 3 showed inhibition activity on LDL oxidation with $IC_{50}$ values of $2.1{\pm}0.2$, $2.4{\pm}0.1$, and $2.0{\pm}0.2\;{\mu}M$, respectively, which are higher activities than that of the positive control, probucol ($6.8{\pm}0.1\;{\mu}M$).

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0