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학술저널
저자정보
Muthuramalingam, Karthika (Department of Biochemistry, School of Medicine, Jeju National University) Singh, Vineet (Faculty of Biotechnology, College of Applied Life Sciences, SARI, Jeju National University) Choi, Changmin (Department of Biochemistry, School of Medicine, Jeju National University) Choi, Seung In (Department of Pharmaceutical Research Institute, Quegen Biotech Co. Ltd.) Park, Sanggyu (Division of Life & Environmental Science, Daegu University) Kim, Young Mee (Department of Biochemistry, School of Medicine, Jeju National University) Unno, Tatsuya (Faculty of Biotechnology, College of Applied Life Sciences, SARI, Jeju National University) Cho, Moonjae (Department of Biochemistry, School of Medicine, Jeju National University)
저널정보
한국응용생명화학회 Journal of applied biological chemistry Journal of applied biological chemistry 제62권 제2호
발행연도
2019.1
수록면
211 - 217 (7page)

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Dietary pattern has paramount importance in shaping the gut microbiota and its associated host health. Herein this study, long term (12 weeks) impact of mushroom derived dietary fiber, ${\beta}-glucan$, is investigated for its effect on low fiber diet consumption. Inclusion of dietary fiber into the low fiber diet (LFD) increased the abundance of genera Lactobacillus and Anaerostipes, the microbes responsible for butyrate (major 'fuel source' of colonocytes) production. Mice fed LFD with ${\beta}-glucan$ showed significant increase in the length of small intestine compared to that of the LFD group without ${\beta}-glucan$. Further, dietary fiber consumption enhanced goblet cell density along with mucosal layer thickness. These results indicate promising effects of ${\beta}-glucan$ towards maintenance of healthy gut and gut microbiota.

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