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학술저널
저자정보
Nemeth, Norbert (Department of Operative Techniques and Surgical Research, Institute of Surgery, Medical and Health Science Center, University of Debrecen) Baskurt, Oguz K. (Department of Physiology, Akdeniz University, Faculty of Medicine) Meiselman, Herbert J. (Department of Physiology, Akdeniz University, Faculty of Medicine) Kiss, Ferenc (Department of Operative Techniques and Surgical Research, Institute of Surgery, Medical and Health Science Center, University of Debrecen) Uyuklu, Mehmet (Department of Physiology, Akdeniz University, Faculty of Medicine) Hever, Timea (Department of Operative Techniques and Surgical Research, Institute of Surgery, Medical and Health Science Center, University of Debrecen) Sajtos, Erika (Department of Operative Techniques and Surgical Research, Institute of Surgery, Medical and Health Science Center, University of Debrecen) Kenyeres, Peter (First Department of Medicine, University of Pec) Toth, Kalman (First Department of Medicine, University of Pec) Furka, Istvan (Department of Operative Techniques and Surgical Research, Institute of Surgery, Medical and Health Science Center, University of Debrece) Miko, Iren
저널정보
한국유변학회 Korea-Australia rheology journal Korea-Australia rheology journal 제21권 제2호
발행연도
2009.1
수록면
127 - 133 (7page)

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Hemorheological results may be influenced by the time between blood sampling and measurement, and storage conditions (e.g., temperature, time) during sample delivery between laboratories may further affect the resulting data. This study examined possible hemorheological alterations subsequent to storage of rat and dog blood at room temperature ($22^{\circ}C$) or with cooling ($4{\sim}10^{\circ}C$) for 2, 4, 6, 24, 48 and 72 hours. Measured hemorheological parameters included hematological indices, RBC aggregation and RBC deformability. Our results indicate that marked changes of RBC deformability and of RBC aggregation in whole blood can occur during storage, especially for samples stored at room temperature. The patterns of deformability and aggregation changes at room temperature are complex and species specific, whereas those for storage at the lower temperature range are much less complicated. For room temperature storage, it thus seems logical to suggest measuring rat and dog cell deformability within 6 hours; aggregation should be measured immediately for rat blood or within 6 hours for dog blood. Storage at lower temperatures allows measuring EI up to 72 hours after sampling, while aggregation must be measured immediately, or if willing to accept a constant decrease, over 24~72 hours.

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