지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한기계학회 Journal of Mechanical Science and Technology Journal of Mechanical Science and Technology Vol.19 No.3
- 발행연도
- 2005.3
- 수록면
- 887 - 893 (7page)
이용수
초록· 키워드
오류제보하기
The aggregability if led blood cells (RBCs) was determined by laser backscattering light analysis in a microfluidic channel Available techniques for RBC aggregation often adopt a rotational Couette-flow using a bob-and-cup system for disaggregating RBCs, which causes the system to be complex and expensive. A disposable microfluidic channel and vibration generating mechanism were used in the proposed new detection system for RBC aggregation Prior to measurement, RBC aggregates in a blood sample were completely disaggregated by the application of Vibration-induced shear With the present apparatus, the aggregation indexes of RBCs can be measured easily with small quantities of a blood sample The measurements with the present aggregometer were compared with those of LORC A and the results showed a strong correlation between them The aggregability of the defibrinogenated blood RBCs is markedly lower than that of the normal RBCs The noble feature of this design is the vibration-induced disaggregation mechanism, which can incorporate the disposable element that holds the blood sample.
목차
Abstract
1. Introduction
2. Materials and Methods
3. Results and Discussions
4. Conclusions
Acknowledgments
References
참고문헌 (14)
참고문헌 신청
Baskurt, O K, Meiselman, H J and Kayar, E, 1998, Measurement of Red Blood Cell Aggregation in a "Plate-Plate" Shearing System by Analysis of Light Transmission, Clin Hemorheol & Microcire Vol 19, pp 307~314
Chien, S, Feng, S, Vayo, M, Sung, L A, Usami, S and Sakalak, R, 1990, "The Dynamics of Shear Disaggregation of Red Blood Cells in a Flow Channel," Biorheology, Vol 27, pp 135~147
Hardeman, M R, Goedhart, P T, Dobbe, J G G and Lettinga, K P, 1994, Laser-Assisted Optical Rotational Cell Analyzer (LORCA) a New Instrument for Measurement of Various Structure Hemorheological Parameters, Clin Hemorheol Vol 14, pp 605~618
Hardeman, M R, Dobbe, J G G and Incc, C, 2001, Thc Laser-Assisted Optical Rotational Cell Analyzer (LORCA) as Red Blood Cell Aggregometer, Clinical Hemorheology and Microcirculation, Vol 25, pp 1~11
Rmapling, M W, 1999 In Cardiovascular Flow Modeling and Measurement with Application to Clinical Medicine, Edited by S G Sajidai, G B Nash and M W Rampling (Clarendon Press, Oxford, pp 183~193
Chien, S, Feng, S, Vayo, M, Sung, L A, Usami, S and Sakalak, R, 1990, "The Dynamics of Shear Disaggregation of Red Blood Cells in a Flow Channel," Biorheology, Vol 27, pp 135~147
Hardeman, M R, Goedhart, P T, Dobbe, J G G and Lettinga, K P, 1994, Laser-Assisted Optical Rotational Cell Analyzer (LORCA) a New Instrument for Measurement of Various Structure Hemorheological Parameters, Clin Hemorheol Vol 14, pp 605~618
Hardeman, M R, Dobbe, J G G and Incc, C, 2001, Thc Laser-Assisted Optical Rotational Cell Analyzer (LORCA) as Red Blood Cell Aggregometer, Clinical Hemorheology and Microcirculation, Vol 25, pp 1~11
Rmapling, M W, 1999 In Cardiovascular Flow Modeling and Measurement with Application to Clinical Medicine, Edited by S G Sajidai, G B Nash and M W Rampling (Clarendon Press, Oxford, pp 183~193
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UCI(KEPA) : I410-ECN-0101-2009-550-014489372