개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 9 - 17 (9page)
이용수
초록· 키워드
오류제보하기
Objectives This study was aimed to evaluate the effects of Daeyoungjeon (hereinafter referred to DYJ) treatment on the injury of articular cartilage induced by monosodium iodoacetate in rats. Methods Twenty-four male rats were divided into normal, osteoarthritic control and DYJ group. Rats of normal group were injected with 0.1 ml physiological saline, rats of control and DYJ groups were injected with 0.1 ml monosodium iodoacetate (3 mg/ml) into each left and right knee joint cavities. Rats of DYJ group were administrated extracts of DYJ during 60 days per orally. At 60 days after treatment, gross lesions, area and proteoglycan contents of articular cartilage, histopathological lesions, immunohistochemistry on matrix metalloproteinases (MMP-2, MMP-3, MMP-7) were evaluated. Results Grossly, degenerative changes of articular cartilages were observed weak in DYJ group. The areas of articular cartilages were broader significantly in DYJ group. The proteoglycan contents in articular cartilages were lesser significantly in DYJ group. Histopathologically, the chondrocyte score was lesser significantly in DYJ group. MMP-3 expression in articular cartilages was observed weak in DYJ group. Conclusions From above results, DYJ treatment has inhibitory effects on the injuries of articular cartilage induced by monosodium iodoacetate in rats, and it's effects may be related with down regulation of MMP-3.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Rosenberg AE / 2010 / Pathologic Basis of Disease / Saunders :1235~1236
Ministry of health, Korea Centers for Disease Control and Prevention / 2013 / Korea Health Statistics 2013: Korea National Health and Nutrition Examination Survey :678~680
Rehabilitation Medicine of Korean Medicine. / 2015 / Korean Rehabilitation Medicine / Kunja Publishing INC :102~116
Zhang Jie-bin / 1999 / Jingyuequashu / Jungdam :1070
Kim KW / 1998 / A study on the effects of Daeyungjeon on ovariectomized osteoporosis of rats / The Korea Jounal of Herbology 13(1):59~81
Ministry of health, Korea Centers for Disease Control and Prevention / 2013 / Korea Health Statistics 2013: Korea National Health and Nutrition Examination Survey :678~680
Rehabilitation Medicine of Korean Medicine. / 2015 / Korean Rehabilitation Medicine / Kunja Publishing INC :102~116
Zhang Jie-bin / 1999 / Jingyuequashu / Jungdam :1070
Kim KW / 1998 / A study on the effects of Daeyungjeon on ovariectomized osteoporosis of rats / The Korea Jounal of Herbology 13(1):59~81
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Monosodium Iodoacetate 유발 골관절염 모델: 장기적인 약물효능 평가에 적합한가?
한방재활의학과학회지
2015 .01
-
증미오비탕이 Monosodium Iodoacetate 유발 관절연골손상에 미치는 영향
대한한의학회지
2020 .09
-
우슬(牛膝) 등 복합 추출물의 monosodium iodoacetate로 유발한 흰쥐 골관절염에 대한 효과
대한본초학회지(본초분과학회지)
2017 .01
-
꽃송이버섯 추출물의 Monosodium Iodoacetate로 유도된 골관절염 억제 효과
생약학회지(Korean Journal of Pharmacognosy)
2018 .09
-
Quantitative T2 Mapping of Articular Cartilage of the Glenohumeral Joint at 3.0T in Rotator Cuff Disease Patients: the Evaluation of Degenerative Change of Cartilage
Investigative Magnetic Resonance Imaging
2019 .01
-
SHP regulates monosodium iodoacetate-induced osteoarthritis in mice
한국실험동물학회 학술발표대회 논문집
2019 .07
-
Proprioception deficiency in articular cartilage lesions of the knee
Knee Surgery and Related Research
2020 .01
-
연골에 대한 줄기세포 치료
대한정형외과학회지
2023 .12
-
Viscum album and its Constituents Downregulate MMP-13 Expression in Chondrocytes and Protect Cartilage Degradation
Natural Product Sciences
2021 .09
-
강황(薑黃) 약침이 Monosodium Iodoacetate 유도 골관절염 흰쥐에 미치는 영향
한방재활의학과학회지
2019 .01
-
족삼리의 선모(仙茅)약침이 Monosodium Iodoacetate로 유발한 골관절염 흰쥐에 미치는 영향
대한침구의학회지
2015 .01
-
Monosodium iodoacetate로 유도된 골관절염 동물모델에서 상기생 물추출물의 효과
대한본초학회지(본초분과학회지)
2018 .01
-
Effects of salmon DNA fraction in vitro and in a monosodium iodoacetate-induced osteoarthritis rat model
The Korean Journal of Physiology & Pharmacology
2018 .03
-
Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes
Biomolecules & Therapeutics(구 응용약물학회지)
2016 .01
-
골관절염에서 줄기세포를 이용한 연골 재생의 최신 지견
대한정형외과학회지
2019 .12
-
Anti-inflammatory Effect of Egg White-chalcanthite and Purple Bamboo Salts Mixture on Arthritis Induced by MIA in Sprague-Dawley Rats
한국실험동물학회 학술발표대회 논문집
2016 .08
-
연산오계(連山烏鷄)가 monosodium iodoacetate로 골관절염(骨關節炎)을 유도(誘導)한 랫드에 미치는 영향(影響)
대한본초학회지(본초분과학회지)
2017 .01
-
무릎 연골 두께 아틀라스를 통한 손상 평가 기법
의공학회지
2015 .01
-
Cryopreservation of Cartilage for Transplantation in Rhinoplasty: A Literature Review
대한이비인후-두경부외과학회지
2016 .01
-
Prevention or treatment of enzyme treated royal jelly on monosodium-iodoacetate-induced osteoarthritis
Journal of Biomedical and Translational Research
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0