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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: This study was carried out to investigate the protective effects of Jeungmiobi-tang on the articular cartilage injuries induced by monosodium iodoacetate in rats.
Methods: Twenty four rats were divided into three groups. Rats of normal group (n=8) were injected with 0.1 ml physiological saline into both knee joint cavities. In the rats of control group (n=8) and Jeungmiobi-tang group (n=8), Arthritis was induced by injecting with 0.1 ml monosodium iodoacetate (5 mg/ml) into both knee joint cavities. After the experiment, Gross and histopathological examinations on the knee joint were performed. The content of proteoglycan in articular cartilage and TNF-α and IL-1β in synovial fluid were also analyzed.
Results: Grossly, Injuries to the articular cartilage surface was observed weak in the Jeungmiobi-tang group compared to the control group. Proteoglycan content in the articular cartilage was significantly higher in the Jeungmiobi-tang group than in the control group. The chondrocyte score was significantly lower in the Jeungmiobi-tang group than in the control group.
Conclusion: According to these results, that Jeungmiobi-tang has protective effects on the articular cartilage injuries induced by monosodium iodoacetate in rats.
Methods: Twenty four rats were divided into three groups. Rats of normal group (n=8) were injected with 0.1 ml physiological saline into both knee joint cavities. In the rats of control group (n=8) and Jeungmiobi-tang group (n=8), Arthritis was induced by injecting with 0.1 ml monosodium iodoacetate (5 mg/ml) into both knee joint cavities. After the experiment, Gross and histopathological examinations on the knee joint were performed. The content of proteoglycan in articular cartilage and TNF-α and IL-1β in synovial fluid were also analyzed.
Results: Grossly, Injuries to the articular cartilage surface was observed weak in the Jeungmiobi-tang group compared to the control group. Proteoglycan content in the articular cartilage was significantly higher in the Jeungmiobi-tang group than in the control group. The chondrocyte score was significantly lower in the Jeungmiobi-tang group than in the control group.
Conclusion: According to these results, that Jeungmiobi-tang has protective effects on the articular cartilage injuries induced by monosodium iodoacetate in rats.
목차
서론
재료 및 방법
결과
고찰
결론
참고문헌
참고문헌 (33)
참고문헌 신청
The Korean Orthopaedic Association / 2013 / Orthopaedics / Choisin publisher :317~322
Rehabilitation Medicine of Korean Medicine / 2015 / Korean Rehabilitation Medicine / Kunja Publishing INC :102~116
Felson DT / 2000 / Osteoarthritis : new insights : part 1 : the disease and its risk factors / Ann Intern Med 133:635~646
Spector TD / 1996 / Genetic influences on osteoarthritis in women : a twin study / BMJ 312:940~943
Greene MA / 2015 / Aging-related inflammation in osteoarthritis / Osteoarthritis Cartilage 23(11):1966~1971
Rehabilitation Medicine of Korean Medicine / 2015 / Korean Rehabilitation Medicine / Kunja Publishing INC :102~116
Felson DT / 2000 / Osteoarthritis : new insights : part 1 : the disease and its risk factors / Ann Intern Med 133:635~646
Spector TD / 1996 / Genetic influences on osteoarthritis in women : a twin study / BMJ 312:940~943
Greene MA / 2015 / Aging-related inflammation in osteoarthritis / Osteoarthritis Cartilage 23(11):1966~1971
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UCI(KEPA) : I410-ECN-0101-2020-519-001162356