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자료유형
학술저널
저자정보
Somchit, M.N. (Department of Biomedical Science, Faculty of Medicine and Health Sciences) Solihah, M.H. (Department of Biomedical Science, Faculty of Medicine and Health Sciences) Israf, D.A. (Department of Biomedical Science, Faculty of Medicine and Health Sciences,Laboratory of Phytomedicines, Institute of Bioscience) Zuraini, A. (Department of Biomedical Science, Faculty of Medicine and Health Sciences) Arifah, A.K. (Department of Pathology and Microbiology, Faculty of Veterinary Medicine) Jais, A.M. Mat (Laboratory of Pharmaceuticals and Nutriceuticals, Institute of Bioscience, Universiti Putra Malaysia)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제4권 제2호
발행연도
2004.1
수록면
91 - 94 (4page)

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Water and chloroform/methanol extracts of the three local Malaysian snakehead fish, Channa striatus (striped snakehead), Channa micropeltes (giant snakehead) and Channa lucius (blotched snakehead) were evaluated for inhibitory activity in chronic inflammation, using cotton pellet granuloma test. Both water extracts of C. striatus and C. micropeltes showed marked inhibition of the transudative and proliferative components of chronic inflammation (42.9 and 31.2% respectively for C. striatus, 35.6 and 26.2% for C. micropeltes) when compared to those of mefenamic acid (25.1 and 21.3% respectively) and piroxicam (36.1 and 26.2% respectively). The chloroform/methanol extracts did not exhibit any anti-inflammatory effects. These results indicated that C. striatus has more anti-transudative and anti-proliferative activities than the extract of C. micropletes. C. lucius extract in contrast, did not inhibit these two components. This present study indicated the beneficial effects of the water extracts of C. striatus and C. micropeltes, but not C. lucius on chronic inflammation.

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