지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제25권 제4호
- 발행연도
- 2002.1
- 수록면
- 550 - 555 (6page)
이용수
초록· 키워드
오류제보하기
The discovery and development of the taxane class of antitumor compounds represent significant advances in the treatment of patients with a variety of malignancies. These drugs are effectively used in the treatment of breast cancer. In this study we evaluated the efficacy of fractionated usage of both paclitaxel and docetaxel as a single agent in the breast cancer cell line MCF-7. It has been shown that the cytotoxic effect of paclitaxel was increased when the divided $IC_{50}$ concentrations were used sequentially and in contrast to paclitaxel, cytotoxic effect of docetaxel was decreased with the same schema and the single dose of $IC_{50}$ concentration was optimal. The cause of the difference between the cytotoxic effects of two agents with this schedule is obscure. Demonstrating mechanisms, which are responsible for these differences, will be important for more rational use of taxoids and to provide basis for the following clinical trials.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Docetaxel versus Paclitaxel Combined with 5-FU and Leucovorin in Advanced Gastric Cancer: Combined Analysis of Two Phase II Trials
Cancer Research and Treatment
2009 .01
-
Potentiation of paclitaxel activity by curcumin in human breast cancer cell by modulating apoptosis and inhibiting EGFR signaling
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2014 .01
-
Response to Paclitaxel in Node-positive Triple Negative Breast Cancer
Annals of Surgical Treatment and Research
2010 .09
-
Arsenic Trioxide Promotes Paclitaxel Cytotoxicity in Resistant Breast Cancer Cells
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Stalility of Paclitaxel with Cephalosporines in 0.8 Sodium Chloride Injection and 5 Dextrose Injection During Simulated Y-Site Administration
한국임상약학회지
2003 .01
-
Clinical Comparison between Paclitaxel Liposome (Lipusu) and Paclitaxel for Treatment of Patients with Metastatic Gastric Cancer
Asian Pacific journal of cancer prevention : APJCP
2013 .01
-
Roles of the Bcl-2/Bax Ratio, Caspase-8 and 9 in Resistance of Breast Cancer Cells to Paclitaxel
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
Anti-tumor Agent, Paclitaxel, Induces de novo Synthesis of Ceramide, Which May Lead to Apoptosis in Human Breast Cancer MCF-7 Cells
대한약학회 학술대회
2001 .01
-
An Anti-cancer Drug, Paclitaxel, Induces Apoptosis in MCF-7 Human Breast, Cancer Cells by Generating Ceramide and Arachidonic Acid
한국응용약물학회 추계학술발표논문집
2002 .01
-
전이성 유방암 환자에서 항암제 Paclitaxel (Taxol®)의 치료효과
Annals of Surgical Treatment and Research
1999 .04
-
Efficacy of Dose Dense Doxorubicin and Cyclophosphamide Followed by Paclitaxel versus Conventional Dose Doxorubicin, Cyclophosphamide Followed by Paclitaxel or Docetaxel in Patients with Node-Positive Breast Cancer
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Development of Polymeric Nanopaclitaxel and Comparison with Free Paclitaxel for Effects on Cell Proliferation of MCF-7 and B16F0 Carcinoma Cells
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
Effect of Ethyl Pyruvate on Paclitaxel-Induced Neuropathic Pain in Rats
The Korean Journal of Pain
2013 .01
-
Establishment of Paclitaxel-resistant Breast Cancer Cell Line and Nude Mice Models, and Underlying Multidrug Resistance Mechanisms in Vitro and in Vivo
Asian Pacific journal of cancer prevention : APJCP
2013 .01
-
Efficacy of Combination Chemotherapy with Paclitaxel and Cisplatin in Patients with Advanced Non-Small Cell LungCancer
Cancer Research and Treatment
2002 .01
-
Proteome Analysis of Differential Protein Expression in Cervical Cancer Cells after Paclitaxel Treatment
Cancer Research and Treatment
2004 .01
-
사람 유방암세포주 MCF-7에 Paclitaxel 처치 후 종양영상용 방사성의약품 섭취 변화에 대한 시험관내 연구
핵의학분자영상
2007 .01
-
Enhanced Paclitaxel Bioavailability after Oral Administration of Paclitaxel Coadministered with Quercetin in Rats.
대한약학회 학술대회
2002 .01
-
An Anti-cancer Drug, Paclitaxel. Induces Apoptosis in MCF-7 Human Breast Cancer Cells by Generating Ceramide and Arachidonic Acid
대한약학회 학술대회
2002 .01
-
Mass Production of Paclitaxel by Plant Cell Culture
대한약학회 학술대회
2000 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0