지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.1
- 수록면
- 1,149 - 1,154 (6page)
이용수
초록· 키워드
오류제보하기
Repeated administration of all addictive drugs, including nicotine, can produce sensitization of extracellular dopamine levels in the nucleus accumbens and behavioral sensitization in rat, as evidenced by an enhanced locomotor response and increased dopamine release in brain to a subsequent injection of the drug. In order to investigate the effect of Zizyphus jujuba extract on repeated nicotin-induced sensitization, rats were given repeated injection of saline or nicotine (0.4 mg/kg s.c., twice a day for 7 d), followed by one challenge injection on the 4th day after the last daily injection. Systemic challenge with nicotine (0.4 mg/kg s.c.) and a direct local challenge of 3 mM a larger increase in locomotor activity and extracellular dopamine release in the nucleus accumbens in nicotine-pretreated rats than in saline-pretreated rats, respectively. Zizyphus jujuba extract significantly decreases locomotor activitiy and dopamine release in the nucleus accumbens induced by a nicotine challenge. These results suggest that Zizyphus jujuba extract may attenuate nicotine-induced neurochemical and behavioral sensitization and may be effective in suppressing compulsive nicotine-seeking behavior.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
산조인 추출물의 니코틴 민감화에 미치는 효과
동의생리병리학회지
2006 .10
-
인삼 사포닌이 흰쥐 측핵과 선조체에서 니코틴에 의한 도파민 유리에 미치는 효과
대한핵의학회지
2002 .01
-
Nicotine Addiction: Neurobiology and Mechanism
Journal of Pharmacopuncture
2020 .01
-
黃芩이 니코틴 중독에 미치는 효과
대한한방소아과학회지
2006 .01
-
Iptakalim Preferentially Decreases Nicotine-induced Hyperlocomotion in Phencyclidine- sensitized Rats: A Potential Dual Action against Nicotine Addiction and Psychosis
Clinical Psychopharmacology and Neuroscience
2012 .01
-
Attenuation of nicotine-induced locomotor sensitization in $\mu$-opioid receptor knockout mice
대한약학회 학술대회
2003 .01
-
중독성 질환으로서의 흡연
신경정신의학
2009 .01
-
Conditioned Place Preference and Self-Administration Induced by Nicotine in Adolescent and Adult Rats
Biomolecules & Therapeutics(구 응용약물학회지)
2014 .01
-
Impact of Nicotine Exposure on Hair Cell Toxicity and Embryotoxicity During Zebrafish Development
Clinical and Experimental Otorhinolaryngology
2018 .01
-
백서 뇌측핵에서 도파민 분비에 대한 침의 효과
대한침구의학회지
2003 .01
-
Nicotine Suppresses TNF-${\alpha}$ Expression in Human Fetal Astrocyte through the Modulation of Nuclear Factor-${\kappa}B$ Activation
Molecular & cellular toxicology
2008 .01
-
생쥐 난자의 체외 성숙에 미치는 Nicotine의 영향
대한불임학회지
2001 .01
-
흡연 당뇨병환자의 흡연정도, 금연행동단계, 니코틴 의존도 및 소변 니코틴에 관한 연구
성인간호학회지
2006 .12
-
The Role of NMDA Receptor Antagonists in Nicotine Tolerance, Sensitization, and Physical Dependence: A Preclinical Review
Yonsei Medical Journal
2008 .01
-
니코틴 중독의 평가와 치료
생물치료정신의학
2002 .06
-
금연 실천과 니코틴 의존도의 변화과정에 관한 연구
보건교육건강증진학회지
2010 .12
-
Airborne Nicotine Concentrations in the Workplaces of Tobacco Farmers
예방의학회지
2014 .01
-
Effect of Acupuncture(PC6) on Behavior, Dopamine Release in the Nucleus Accumbens in Rats Sensitized to Morphine
대한동의병리학회 학술대회논문집
2005 .08
-
Antinociceptive Effect of Nicotine in Various Pain Models in the Mouse
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
-
Inhibitory Effect of Nicotine on Apoptosis Induced by Endoplasmic Reticulum Stress
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2007 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0