지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Genistein was tested for chemopreventive potential against breast cancer by measuring the effect on proliferation of human breast cancer cells, human placental aromatase activity and cyclooxygenases-2 (COX-2) expression and activity, Genistein inhibited the growth of estrogen-independent MDA-MB-231 human breast cancer cell. However, there is no inhibitory effect of genistein on human placental aromatase activity. The expression of COX-2 was inhibited by genistein in Western blot analysis. Genistein significantly inhibited COX-2 activity at the concentrations of 10 (p<0.05), 25 (p<0.05) and 50 ${\mu}M$ (p<0.01). These results suggest that genistein may have breast cancer chemopreventive potential by inhibiting the growth of human breast cancer cell and expression and activity of COX-2.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Genistein이 유방암예방 활성에 미치는 영향
동의생리병리학회지
2006 .02
-
Chemopreventive and chemotherapeutic effects of genistein, a soy isoflavone, upon cancer development and progression in preclinical animal models
Laboratory Animal Research
2014 .12
-
GENISTEIN INHIBITS $NF-_kB-DEPENDENT$ COX-2 INDUCTION IN HUMAN BREAST EPITHELIAL CELLS BY MODULATING THE ACTIVATION OF TATA-BINDING PROTEIN
대한약학회 학술대회
2002 .01
-
미성숙 암컷 흰쥐의 성 성숙에 미치는 genistein의 효과
Clinical and Experimental Pediatrics
2009 .01
-
Molecular Effects of Genistein on Proliferation and Apoptosis of MCF-7 Cell Line
Molecular & cellular toxicology
2006 .01
-
Genistein이 햄스터 난소세포의 항산화효소활성과 발현에 미치는 영향
약학회지
2007 .01
-
Synthesizing efficacious genistein in conjugation with superparamagnetic Fe3O4 decorated with bio-compatible carboxymethylated chitosan against acute leukemia lymphoma
생체재료학회지
2020 .01
-
Effect of Genistein on the Aryl Hydrocarbon Receptor and Cytochrome P450 1A1 in MCF-7 Human Breast Carcinoma Cells
Environmental Analysis Health and Toxicology
2006 .03
-
Pharmaceutical Evaluation of Genistein-loaded Pluronic Micelles for Oral Delivery
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Genistein from Vigna angularis Extends Lifespan in Caenorhabditis elegans
Biomolecules & Therapeutics(구 응용약물학회지)
2015 .01
-
Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice
한국실험동물학회 학술발표대회 논문집
2013 .08
-
Genistein 에 의한 B35 신경모세포종 세포의, 세포자멸사유도 및 세포주기 정지; p21waf1/cip1, Bax와 Bcl-2의 관련
Journal of Pathology and Translational Medicine
2006 .01
-
EFFECTS OF GENISTEIN ON EXPRESSION OF COX-2 AND ACTIVATION OF ERK 1/2 INDUCED BY PHORBOL ESTER AND TNF-${\alpha}$ IN CULTURED HUMAN BREAST EPITHELIAL CELLS
대한약학회 학술대회
2002 .01
-
Preferential Cytotoxic Effect of Genistein on G361 Melanoma Cells Via Inhibition of the Expression of Focal Adhesion Kinase
International Journal of Oral Biology
2012 .01
-
Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice
한국실험동물학회 학술발표대회 논문집
2012 .08
-
Genistein이 T lymphocyte의 Apoptosis 및 복강 Macrophage의 탐식능에 미치는 영향
약학회지
2002 .01
-
Effect of genistein administration on the recovery of spermatogenesis in the busulfan-treated rat testis
Clinical and experimental reproductive medicine : CERM
2013 .01
-
Osteogenic Activities of Genistein Derivatives were Influenced by the Presence of Prenyl Group at Ring A
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2008 .01
-
Breast Cancer
대한외과학회 학술대회 초록집
2019 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0