간외담도폐쇄에 대한 Kasai 술식 후 생존 결과 및 예후인자

윤찬석; 한석주; 박영년; 정기섭; 오정탁; 최승훈

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자료유형: 학술저널

저자정보: 윤찬석 (강북삼성병원 외과) 한석주 (연세의대 외과학교실) 박영년 (연세의대 병리학교실) 정기섭 (연세의대 소아과교실) 오정탁 (연세의대 외과학교실) 최승훈 (연세의대 외과학교실)

저널정보: 대한소아외과학회 Journal of the Korean Association of Pediatric Surgeons : JKAPS Journal of the Korean Association of Pediatric Surgeons : JKAPS 제12권 제2호

발행연도: 2006.1

수록면: 202 - 212 (11page)

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The prognostic factors for extrahepatic biliary atresia (EHBA) after Kasai portoenterostomy include the patient's age at portoenterostomy (age), size of bile duct in theporta hepatis (size), clearance of jaundice after operation (clearance) and the surgeon's experience. The aim of this study is to examine the most significant prognostic factor of EHBA after Kasai portoenterostomy. This retrospective study was done in 51 cases of EHBA that received Kasai portoenterostomy by one pediatric surgeon. For the statistical analysis, Kaplan-Meier method, Logrank test and Cox regression test were used. A p value of less than 0.05 was considered to be significant. Fifteen patients were regarded as dead in this study, including nine cases of liver transplantation. There was no significant difference of survival to age. The age is also not a significant risk factor for survival in this study (Cox Regression test; p = 0.63). There was no significant difference in survival in relation to the size of bile duct. However, bile duct size was a significant risk factor for survival (Cox Regression test; p = 0.002). There was a significant difference in relation to survival and clearance (Kaplan-Meier method; p = 0.02). The clearing was also a significant risk factor for survival (Cox Regression test; p = 0.001). The clearance of jaundice is the most significant prognostic factor of EHBA after Kasai portoenterostomy.

#Biliary atresia #Portoenterostomy #Survival #Prognosis

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