지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.5
- 수록면
- 355 - 361 (7page)
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초록· 키워드
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Purpose: Patients with biliary atresia (BA) treated with Kasai portoenterostomy may later develop intractable cholangitis (IC) that is unresponsive to routine conservative treatment. It may cause biliary cirrhosis and eventually hepatic failure with portal hypertension. Control of IC requires prolonged hospitalization for the administration of intravenous antibiotics. To reduce the hospitalization period, we designed a home intravenous antibiotic treatment (HIVA) which can be administered after initial inpatient treatment. In this study, we reviewed the effects of this treatment. Methods: We reviewed medical records of 10 patients treated with HIVA for IC after successful Kasai portoenterostomies performed for BA between July 1997 and June 2009. Results: The duration of HIVA ranged from 8 to 39 months (median, 13.5 months). The median length of hospital stay was 5.7 days per month for conventional treatments to manage IC before HIVA and, 1.5 days per month (P = 0.012) after HIVA. The median amount of medical expenses per month was reduced by about one tenth with HIVA. One patient underwent liver transplantation due to uncontrolled esophageal variceal bleeding, but the other nine patients had acceptable hepatic function with native livers. Conclusion: HIVA may be an effective primary treatment for IC after Kasai portoenterostomies for BA, and reduce length of hospital stay and medical expense.
목차
Purpose
INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONFLICTS OF INTEREST
REFERENCES
참고문헌 (12)
참고문헌 신청
1. [학술지(정기간행물)] - Ecoffey C / 1987 / Bacterial cholangitis after surgery for biliary atresia / J Pediatr 111 (6 Pt 1) : 824 ~ 829
2. [학술지(정기간행물)] - Ernest van Heurn LW / 2003 / Cholangitis after hepatic portoenterostomy for biliary atresia: a multivariate analysis of risk factors / J Pediatr 142 : 566 ~ 571
3. [학술지(정기간행물)] - Luo Y / 2008 / Current concept about postoperative cholangitis in biliary atresia / World J Pediatr 4 : 14 ~ 19
4. [학술지(정기간행물)] - Nakama T / 1991 / Ultrasonographic findings and management of intrahepatic biliary tract abnormalities after portoenterostomy / J Pediatr Surg 26 : 32 ~ 36
5. [학술지(정기간행물)] - Tsuchida Y / 1994 / Cystic dilatation of the intrahepatic biliary system in biliary atresia after hepatic portoenterostomy / J Pediatr Surg 29 : 630 ~ 634
2. [학술지(정기간행물)] - Ernest van Heurn LW / 2003 / Cholangitis after hepatic portoenterostomy for biliary atresia: a multivariate analysis of risk factors / J Pediatr 142 : 566 ~ 571
3. [학술지(정기간행물)] - Luo Y / 2008 / Current concept about postoperative cholangitis in biliary atresia / World J Pediatr 4 : 14 ~ 19
4. [학술지(정기간행물)] - Nakama T / 1991 / Ultrasonographic findings and management of intrahepatic biliary tract abnormalities after portoenterostomy / J Pediatr Surg 26 : 32 ~ 36
5. [학술지(정기간행물)] - Tsuchida Y / 1994 / Cystic dilatation of the intrahepatic biliary system in biliary atresia after hepatic portoenterostomy / J Pediatr Surg 29 : 630 ~ 634
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UCI(KEPA) : I410-ECN-0101-2013-514-002684211