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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 저널정보
- 대한약학회 대한약학회 학술대회 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
- 발행연도
- 2002.1
- 수록면
- 2,282 - 2,283 (2page)
이용수
이 논문의 연구 히스토리 (3)
2002
The Differential Roles of Glutamine Synthetase in Methylmercury Neurotoxicity
Pa
,
k
,
Young-Jin
외 4명
대한약학회 학술대회
2002.01
학술대회자료
Role of Increases of Glutamine Synthetase in Primary Culture of Mixed Gilal Cells (MGC) and Purified Astrocytes (AST) on Methylmercury Toxicity
Pa
,
k
,
Young-Jin
외 4명
대한약학회 학술대회
2002.01
학술대회자료
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Methylmercury (MeHg). a potent neurotoxicant. produces neuronal death that may be partially mediated by glutamate. Glutamine synthetase (GS), a glial-specific enzyme. catalyzes the synthesis of glutamine from glutamate and ammonia and is associated with ischemic injury and neurological diseases. Objectives of this experiment are to investigate whether in vivo and in vitro MeHg exposure have adverse effects on GS and whether duration of exposure to MeHg and glutamate co-treatment playa role in MeHg-induced toxicity. (omitted)
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