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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2002.1
- 수록면
- 28 - 28 (1page)
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Peptidoglycan is an extensively cross-linked polymer essential for the integrity of the bacterial cell wall. Many antibiotics act by disruption of its biosynthesis and assembly, several are targeted against the cytoplasmic enzymes that synthesize the key intermediate UDP-N-acetylmuramyl pentapeptide. One such drug is fosfomycin, which inactivates the first enzymes in this pathway, UDP-N-acetylglucosamine enopyruvyl transferase (murZ).(omitted)
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