지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 저널정보
- 한국응용약물학회 한국응용약물학회 추계학술발표논문집 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
- 발행연도
- 2003.1
- 수록면
- 89 - 89 (1page)
이용수
이 논문의 연구 히스토리 (2)
2003
Regulation of CYP 1A1 gene expression by retinoic acid receptor, retinoid X receptor and constitutive androstane receptor in rainbow trout hepatoma cells(RTH 149)
Kim
,
Ji-Sun
,
Yang
외 5명
대한약학회 학술대회
2003.01
학술대회자료
Regulation of CYP 1A1 gene expression by retinoic acid receptor, retinoid X receptor and constitutive androstane receptor in rainbow trout hepatoma cells(RTH 149)
Kim
,
Ji-Sun
,
Yang
외 5명
한국응용약물학회 추계학술발표논문집
2003.01
학술대회자료
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Exposure of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a variety of biological and toxicology effects, most of which are mediated by aryl hydrocarbon receptor (AhR). The ligand-bound AhR as a heterodimer with AhR nuclear translocator (ARNT) binds to its specific DNA recognition site, the dioxin-responsive element (DRE), and it results in increased transcription of CYP1A1 gene. Retinoic acid (RA) regulates the transcription of various genes for several essential functions through binding to two classes of nuclear receptors, the retinoic acid receptor (RAR) and retinoid X receptor (RXR). Constitutive androstane receptor (CAR) also regulates the transcription of gene. In this study, we have examined how RAR, RXR and CAR regulated CYP1A1 in rainbow trout hepatoma cell (RTH 149) using luciferase reporter gene assay system. We did transient transfection with CYP1A1 luciferase reporter gene and treated with TCDD, all-trans RA, 9-cis RA and phenobarbital. Treatment of all-trans RA, 9-cis RA or phenobarbital decreased the TCDD induced transcription of CYP1Al. When we did transient cotransfection with CYP1A1 luciferase reporter gene and RXR, as increase of RXR concentration, the TCDD induced transcription of CYP1A1 was decreased. Transfection with CAR also decreased the TCDD induced transcription of CYP1A1 in RTH 149 cells.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Regulation of CYP 1A1 gene expression by retinoic acid receptor, retinoid X receptor and constitutive androstane receptor in rainbow trout hepatoma cells(RTH 149)
대한약학회 학술대회
2003 .01
-
Regulation of CYP 1A1 gene expression by retinoic acid receptor, retinoid X receptor and constitutive androstane receptor in rainbow trout hepatoma cells(RTH 149)
환경독성보건학회 심포지엄 및 학술대회
2003 .10
-
Regulation of CYP 1A transcription level and enzyme activity by retinoic acids in rainbow trout hepatoma cells(RTH 149)
환경독성보건학회 심포지엄 및 학술대회
2004 .05
-
ARYL HYDROCARBON- AND ESTROGEN-MEDIATED SIGNALS POSSIBLY CROSS TALK TO REGULATE CYP1A1 GENE EXPRESSION
한국응용약물학회 추계학술발표논문집
2001 .01
-
Suppression of CYP1A1 Expression by Naringenin in Murine Hepa-1c1c7 Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Retinoid regulation of CYP1A expression and EROD activity by retinoic acids in rainbow trout hepatoma (RTH 149) and mouse liver cells (Hepa 1c1c7)
환경독성보건학회 심포지엄 및 학술대회
2004 .11
-
Cytochrome P-450 3A4 proximal promoter activity by histone deacetylase inhibitor in HepG2 cell.
한국응용약물학회 추계학술발표논문집
2003 .01
-
Environmental Estrogen effects on the TCDD stimulated CYP1A1 expression
대한약학회 학술대회
2001 .01
-
Induction of Phase I, II and III Drug Metabolism/Transport by Xenobiotics
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
-
Effects of CYP1A2$^*$1C and CYP1A2$^*$1F Genotypes on the Activity and Inducibility of CYP1A2 Determined by Urinary Caffeine Metabolite Ratio in Koreans
Molecular & cellular toxicology
2007 .01
-
Analysis of CYP17, CYP19 and CYP1A1 Gene Polymorphisms in Iranian Women with Breast Cancer
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Identification of Differentially Expressed Genes by TCDD in Human Bronchial Cells : Toxicogenomic Markers for Dioxin Exposure
대한의생명과학회지
2012 .03
-
Changes in Gene Expression by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in the Liver of C57BL/6 Mice
Laboratory Animal Research
2005 .12
-
CYP2E15B, CYP2E16, CYP2E17B, CYP2E12, and CYP2E13 Allele Frequencies in Iranian Populations
Asian Pacific journal of cancer prevention : APJCP
2012 .01
-
Expression of CYP2A6, CYP2D6 and CYP4A11 Polymorphisms in COS7 Mammalian Cell Line
Toxicological Research
2011 .03
-
Effect of HDAC inhibitors on the Ah Receptor mediated CYP1A1 transcription
환경독성보건학회 심포지엄 및 학술대회
2004 .05
-
CYP2E1과 CYP2C19 유전자 다형성이 위암 발생 감수성에 미치는 영향
Annals of Surgical Treatment and Research
2007 .08
-
Effects of Korean traditional herbal formula for common cold on the activities of human CYP450 isozymes
대한한의학회지
2014 .06
-
The effects of estradiol and its metabolites on the regulation of CYP 1A1 expression.
대한약학회 학술대회
2002 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0