지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.99 No.2
- 발행연도
- 2020.8
- 수록면
- 82 - 89 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: The management of patients with colorectal cancer (CRC) who have liver cirrhosis (LC) requires a thorough understanding of both diseases; however, the prognoses and postoperative outcomes of such patients remain understudied. We investigated the effect of LC on surgical and oncologic outcomes in patients with CRC, and identified prognostic factors.
Methods: We analyzed 453 patients with CRC and LC (CRC-LC group), 906 with CRC only (CRC group), 906 with LC only (LC group), and 1,812 healthy subjects using health insurance claim data (2008–2013).
Results: The CRC-LC group had a higher frequency of intensive care unit admission than the CRC group; there were no differences between the 2 groups in terms of early and late postoperative small bowel obstruction and incisional hernia. However, the 30-day, 60-day, and 90-day mortality rates were all significantly higher in the CRC-LC group. The higher Charlson comorbidity index (hazard ratio [HR], 1.127) and the lower socioeconomic status (HR, 0.985) were significant worse predictors of 5-year survival. Patients with underlying LC had a significantly higher HR in both the advanced CRC (HR, 1.858) and nonadvanced CRC (HR, 1.799) subgroups. However, the nonadvanced CRC subgroup showed a lower HR than the LC group (HR, 0.730).
Conclusion: Patients with CRC who had underlying LC had a lower survival rate than did those without LC, although the incidence rates of postoperative complications were not significantly different. The presence of LC was associated with a significantly lower survival rate regardless of CRC presence.
Methods: We analyzed 453 patients with CRC and LC (CRC-LC group), 906 with CRC only (CRC group), 906 with LC only (LC group), and 1,812 healthy subjects using health insurance claim data (2008–2013).
Results: The CRC-LC group had a higher frequency of intensive care unit admission than the CRC group; there were no differences between the 2 groups in terms of early and late postoperative small bowel obstruction and incisional hernia. However, the 30-day, 60-day, and 90-day mortality rates were all significantly higher in the CRC-LC group. The higher Charlson comorbidity index (hazard ratio [HR], 1.127) and the lower socioeconomic status (HR, 0.985) were significant worse predictors of 5-year survival. Patients with underlying LC had a significantly higher HR in both the advanced CRC (HR, 1.858) and nonadvanced CRC (HR, 1.799) subgroups. However, the nonadvanced CRC subgroup showed a lower HR than the LC group (HR, 0.730).
Conclusion: Patients with CRC who had underlying LC had a lower survival rate than did those without LC, although the incidence rates of postoperative complications were not significantly different. The presence of LC was associated with a significantly lower survival rate regardless of CRC presence.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (23)
참고문헌 신청
Tsochatzis EA / 2014 / Liver cirrhosis / Lancet 383:1749~1761
Han EC / 2017 / Oncologic and surgical outcomes in colorectal cancer patients with liver cirrhosis : a propensity-matched study / PLoS One 12:e0178920
Friedman LS / 2010 / Surgery in the patient with liver disease / Trans Am Clin Climatol Assoc 121:192~204
Nguyen GC / 2009 / The impact of cirrhosis and portal hypertension on mortality following colorectal surgery : a nationwide, population-based study / Dis Colon Rectum 52:1367~1374
Lopez-Delgado JC / 2016 / Outcomes of abdominal surgery in patients with liver cirrhosis / World J Gastroenterol 22:2657~2667
Han EC / 2017 / Oncologic and surgical outcomes in colorectal cancer patients with liver cirrhosis : a propensity-matched study / PLoS One 12:e0178920
Friedman LS / 2010 / Surgery in the patient with liver disease / Trans Am Clin Climatol Assoc 121:192~204
Nguyen GC / 2009 / The impact of cirrhosis and portal hypertension on mortality following colorectal surgery : a nationwide, population-based study / Dis Colon Rectum 52:1367~1374
Lopez-Delgado JC / 2016 / Outcomes of abdominal surgery in patients with liver cirrhosis / World J Gastroenterol 22:2657~2667
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Attitudes Towards Colorectal Cancer (CRC) and CRC Screening Tests among Elderly Malay Patients
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Chasm between Public Perceptions and Epidemiological Data on Colorectal Cancer
Gut and Liver
2023 .05
-
Assessment of Jordanian Patient's Colorectal Cancer Awareness and Preferences towards CRC Screening: Are Jordanians Ready to Embrace CRC Screening?
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Optimal Starting Age for Colorectal Cancer Screening in an Era of Increased Metabolic Unhealthiness: A Nationwide Korean Cross-Sectional Study
Gut and Liver
2018 .01
-
Comparison of oncologic outcomes between patients with Lynch syndrome and sporadic microsatellite instability-high colorectal cancer
Annals of Surgical Treatment and Research
2021 .07
-
대장암 환자의 생활습관 개선 영향요인
성인간호학회지
2019 .06
-
Factors Affecting Adherence to National Colorectal Cancer Screening: A 12-Year Longitudinal Study Using Multi-Institutional Pooled Data in Korea
Journal of Korean Medical Science
2024 .01
-
MicroRNA-362 Inhibits Cell Proliferation and Invasion by Directly Targeting SIX1 in Colorectal Cancer
Yonsei Medical Journal
2019 .01
-
Characteristics of Young Colorectal Cancer in Brunei Darussalam: an Epidemiologic Study of 29 Years (1986-2014)
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Clinicopathologic Characteristics of Young-Onset Colorectal Cancer
대한임상종양학회 학술대회지
2021 .06
-
Association of Measures of Glucose Metabolism with Colorectal Cancer Risk in Older Chinese: A 13-Year Follow-up of the Guangzhou Biobank Cohort Study-Cardiovascular Disease Substudy and Meta-Analysis
Diabetes and Metabolism Journal
2024 .01
-
Risk of Death in Colorectal Cancer Patients with Multi-morbidities of Metabolic Syndrome: A Retrospective Multicohort Analysis
Cancer Research and Treatment
2021 .01
-
Validation of Administrative Big Database for Colorectal Cancer Searched by International Classification of Disease 10th Codes in Korean: A Retrospective Big-cohort Study
대한암예방학회지
2018 .01
-
The Risk of Colorectal Cancer After Cholecystectomy or Appendectomy: A Population-based Cohort Study in Korea
예방의학회지
2018 .01
-
전이성 대장암의 외과적 치료
대한의사협회지
2022 .09
-
Knowledge and Perceptions about Colorectal Cancer in Jordan
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Clinicopathologic characteristics and survival of patients with double primary malignancies: breast and colorectal cancer
Annals of Coloproctology
2022 .06
-
Clinical and Biological Features of Interval Colorectal Cancer
Clinical Endoscopy
2017 .01
-
Characteristics of minute T1 colorectal cancer in relevance to pathology and treatment
Annals of Surgical Treatment and Research
2020 .04
-
Exploring the nexus between obesity, metabolic syndrome, and colorectal cancer
고신대학교 의과대학 학술지
2024 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2020-514-001100182