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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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Purpose: We studied the impact of arterial oxygen tension (PaO2) on the long term neurologic outcome in patients with acute carbon monoxide poisoning. Methods: The study population included 311 patients who presented to emergency department with acute CO poisoning from January 2015 to January 2018. These patients underwent arterial blood gas testing at the time of presentation. The baseline demographic, clinical, laboratory, and clinical outcome data were recorded. The primary outcome of interest was the long term neurologic status. Results: The normoxia group was significantly older and it had a higher incidence of diffusion weighted MRI abnormality, and this group needed multiple HBO sessions compared to the group with moderate or severe hyperoxia. Also, the incidence of altered mentality at discharge was higher in the normoxia group than that of the moderate hyperoxia group. The incidence of a poor long term neurologic outcome was 11.3%. The incidence of a poor long term neurologic outcome decreased as the PaO2 increased. The PaO2 was significantly lower in patients with a poor long term neurologic outcome than that of the patients with a good outcome 198 (165.2 to 231.1) mmHg in the good outcome group vs. 154 (119-162) mmHg in poor outcome, p<0.001). In multivariate logistic regression analysis, PaO2 was selected as an independent factor of the poor long-term neurologic outcome (OR 0.981 (95% CI: 0.968 to 0.995)) Conclusion: Higher PaO2 was independently associated with a lower incidence of a poor long-term neurologic outcome.
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참고문헌 (21)
참고문헌 신청
Hampson NB / 2016 / U. S. mortality due to carbon monoxide poisoning, 1999-2014 : accidental and intentional deaths / Ann Am Thorac Soc 13:1768~1774
Hampson NB / 2013 / Toxic CO-ingestions in intentional carbon monoxide poisoning / J Emerg Med 44:625~630
Mott JA / 2002 / National vehicle emissions policies and practices and declining US carbon monoxiderelated mortality / JAMA 288:988~995
Hsiao CL / 2004 / Delayed encephalopathy after carbon monoxide intoxication-long-term prognosis and correlation of clinical manifestations and neuroimages / Acta Neurol Taiwan 13:64~70
Hampson NB / 2012 / Practice recommendations in the diagnosis, management, and prevention of carbon monoxide poisoning / Am J Respir Crit Care Med 186:1095~1101
Hampson NB / 2013 / Toxic CO-ingestions in intentional carbon monoxide poisoning / J Emerg Med 44:625~630
Mott JA / 2002 / National vehicle emissions policies and practices and declining US carbon monoxiderelated mortality / JAMA 288:988~995
Hsiao CL / 2004 / Delayed encephalopathy after carbon monoxide intoxication-long-term prognosis and correlation of clinical manifestations and neuroimages / Acta Neurol Taiwan 13:64~70
Hampson NB / 2012 / Practice recommendations in the diagnosis, management, and prevention of carbon monoxide poisoning / Am J Respir Crit Care Med 186:1095~1101
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