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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제17권 제4호
- 발행연도
- 2019.1
- 수록면
- 559 - 563 (5page)
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Schizophrenic patients resistant to antipsychotics are diagnosed as having treatment-refractory schizophrenia, and they are treated with clozapine. However, clozapine is sometimes combined with electroconvulsive therapy (ECT) if clozapine monotherapy fails. In this report, a severe treatment-refractory schizophrenic patient who did not respond to clozapine even with ECT, but who recovered with asenapine monotherapy, is presented. Asenapine, considered a serotonin spectrum dopamine modulator, is a new atypical antipsychotic with unique pharmacological features that is used not only for schizophrenia, but also for bipolar disorder. The unique features of asenapine may be effective for some treatment- refractory schizophrenic patients.
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등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Ajnakina O / 2018 / Validation of an algorithm-based definition of treatment resistance in patients with schizophrenia / Schizophr Res 197:294~297
National Institute for Health and Care Excellence / Psychosis and schizophrenia in adults: prevention and management / NICE
Kane J / 1988 / Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine / Arch Gen Psychiatry 45:789~796
Meltzer HY / 2012 / Clozapine : balancing safety with superior antipsychotic efficacy / Clin Schizophr Relat Psychoses 6:134~144
Ahmed S / 2017 / Combined use of electroconvulsive therapy and antipsychotics(both clozapine and non-clozapine)in treatment resistant schizophrenia : a comparative meta-analysis / Heliyon 3:e00429
National Institute for Health and Care Excellence / Psychosis and schizophrenia in adults: prevention and management / NICE
Kane J / 1988 / Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine / Arch Gen Psychiatry 45:789~796
Meltzer HY / 2012 / Clozapine : balancing safety with superior antipsychotic efficacy / Clin Schizophr Relat Psychoses 6:134~144
Ahmed S / 2017 / Combined use of electroconvulsive therapy and antipsychotics(both clozapine and non-clozapine)in treatment resistant schizophrenia : a comparative meta-analysis / Heliyon 3:e00429
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