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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 227 - 234 (8page)
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초록· 키워드
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Background: Because there is limited recent information on this topic, this study investigated the seroprevalence of anti-hepatitis A virus (HAV) immunoglobulin G (IgG) in the South Korean population in 2015–2017. Methods: Anti-HAV IgG seroprevalence data were obtained from the laboratory information system of Green Cross Laboratories, one of the largest referral laboratories in South Korea. Results: During the three-year study period, we obtained test results from 240,840 individuals (124,353 men and 116,487 women) from 1,348 hospitals and local clinics throughout South Korea. The median (range) age of subjects was 38.0 (18.0–97.2) years. The annual seroprevalence of anti-HAV IgG was 53.3%, 53.0%, and 53.1% in 2015, 2016, and 2017, respectively. The median age differed among geographic regions and anti-HAV seroprevalence differed among age groups and geographic regions (P<0.0001). Subjects in their 20’s had a significantly lower rate of anti-HAV IgG-positivity than subjects in their 10’s (odds ratio, [OR] 0.74, 95% CI, 0.69–0.78, P<0.0001), while other age groups had higher rates. Multivariable-adjusted logistic regression analysis showed that women and subjects living in Inchoen, Sejong city, Gangwon province, Gwangju, and North Jeolla province were more likely to be immune to HAV compared to subjects living in Seoul (OR >1.0, P<0.05). Conclusions: This study provides basic information about the recent seroprevalence of anti-HAV IgG in the Korean population and contributes to identifying groups at high risk of an HAV epidemic.
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참고문헌 (15)
참고문헌 신청
Lemon SM / 2018 / Type A viral hepatitis : A summary and update on the molecular virology, epidemiology, pathogenesis and prevention / J Hepatol 68:167~184
GBD 2013 Mortality and Causes of Death Collaborators / 2015 / Global, regional, and national age-sex speciflc all-cause and cause-speciflc mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013 / Lancet 385:117~171
Yoon JG / 2017 / Seroprevalence and disease burden of acute hepatitis A in adult population in South Korea / PLoS One 12:e0186257
Korea Centers for Disease Control and Prevention / Changing patterns of hepatitis A virus infection in Korea. Public Health Weekly Report
이현주 / 2011 / Seroepidemiology of Hepatitis A in Korea: Changes over the Past 30 Years / Journal of Korean Medical Science 26(6):791~796
GBD 2013 Mortality and Causes of Death Collaborators / 2015 / Global, regional, and national age-sex speciflc all-cause and cause-speciflc mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013 / Lancet 385:117~171
Yoon JG / 2017 / Seroprevalence and disease burden of acute hepatitis A in adult population in South Korea / PLoS One 12:e0186257
Korea Centers for Disease Control and Prevention / Changing patterns of hepatitis A virus infection in Korea. Public Health Weekly Report
이현주 / 2011 / Seroepidemiology of Hepatitis A in Korea: Changes over the Past 30 Years / Journal of Korean Medical Science 26(6):791~796
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