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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 566 - 571 (6page)
이용수
초록· 키워드
오류제보하기
ELISAs and rapid diagnostic tests (RDTs) are widely used for diagnosing dengue virus (DENV) infection. Using 138 single blood samples, we compared the ability to detect non-structural (NS)-1 antigen and anti-DENV IgM/IgG antibodies among (1) DENV Detect NS1 ELISA, DENV Detect IgM capture ELISA and DENV Detect IgG ELISA (InBios International, Inc.); (2) Anti-Dengue virus IgM Human ELISA and Anti-Dengue virus IgG Human ELISA (Abcam); (3) Dengue virus NS1 ELISA, Anti-Dengue virus ELISA (IgM) and Anti-Dengue virus ELISA (IgG) (Euroimmun); (4) Asan Easy Test Dengue NS1 Ag 100 and Asan Easy Test Dengue IgG/IgM (Asan Pharm); (5) SD BIOLINE Dengue Duo (Standard Diagnostics); and (6) Ichroma Dengue NS1 and Ichroma Dengue IgG/IgM (Boditech Med). For NS1 antigen detection, InBios and Euroimmun showed higher sensitivities (100%) than the RDTs (42.9–64.3%). All tests demonstrated variable sensitivities for IgM (38.1–90.5%) and IgG (65.7–100.0%). InBios and Boditech Med demonstrated higher sensitivity (95.6% and 88.2%, respectively) than the other tests for combined NS1 antigen and IgM antibody. Five NS1 antigen tests had good agreement (92.8–98.6%) without showing positivity for chikungunya. However, all IgG tests demonstrated potential false-positivity with variable ranges. Clinical laboratories should note performance variations across tests and potential cross-reactivity.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
World Health Organization / Dengue guidelines for diagnosis, treatment, prevention and control: new edition
Muhammad Suleman / 2017 / Dengue Virus Serotypes Circulating in Khyber Pakhtunkhwa Province, Pakistan, 2013-2015 / Annals of Laboratory Medicine 37(2):151~154
Blacksell SD / 2011 / Evaluation of six commercial point-of-care tests for diagnosis of acute dengue infections : the need for combining NS1 antigen and IgM/IgG antibody detection to achieve acceptable levels of accuracy / Clin Vaccine Immunol 18:2095~2101
Fatima A / 2015 / Review : progress in the diagnosis of dengue virus infections and importance of point of care test : a review / Pak J Pharm Sci 28:271~280
Dussart P / 2006 / Evaluation of an enzyme immunoassay for detection of dengue virus NS1 antigen in human serum / Clin Vaccine Immunol 13:1185~1189
Muhammad Suleman / 2017 / Dengue Virus Serotypes Circulating in Khyber Pakhtunkhwa Province, Pakistan, 2013-2015 / Annals of Laboratory Medicine 37(2):151~154
Blacksell SD / 2011 / Evaluation of six commercial point-of-care tests for diagnosis of acute dengue infections : the need for combining NS1 antigen and IgM/IgG antibody detection to achieve acceptable levels of accuracy / Clin Vaccine Immunol 18:2095~2101
Fatima A / 2015 / Review : progress in the diagnosis of dengue virus infections and importance of point of care test : a review / Pak J Pharm Sci 28:271~280
Dussart P / 2006 / Evaluation of an enzyme immunoassay for detection of dengue virus NS1 antigen in human serum / Clin Vaccine Immunol 13:1185~1189
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