Serologic Tests of IgG and IgM Antibodies and IgG Avidity for Diagnosis of Ocular Toxoplasmosis

Bahman Rahimi-Esboei; Mohammad Zarei; Mehdi Mohebali; Hossein Keshavarz Valian; Saeedeh Shojaee; Raziyeh Mahmoudzadeh; Mirataollah Salabati

추천

검색

질문

자료유형: 학술저널

저자정보: Bahman Rahimi-Esboei (Tehran University of Medical Sciences) Mohammad Zarei (Tehran University of Medical Sciences) Mehdi Mohebali (Tehran University of Medical Sciences) Hossein Keshavarz Valian (Tehran University of Medical Sciences) Saeedeh Shojaee (Tehran University of Medical Sciences) Raziyeh Mahmoudzadeh (Tehran University of Medical Sciences) Mirataollah Salabati (Tehran University of Medical Sciences)

저널정보: 대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.56 No.2

발행연도: 2018.4

수록면: 147 - 152 (6page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

This prospective study was aimed to detect acute and chronic ocular toxoplasmosis by comparison of anti-Toxoplasma gondii IgM and IgG antibody levels and IgG avidity test. One hundred and seventeen patients with ocular toxoplasmosis (OT) who referred to the Farabi Eye Hospital, Tehran, Iran were included in this study. Of the patients, 77 cases were positive for anti-T. gondii IgG, and 8 cases were positive for anti-T. gondii IgM. IgG avidity test revealed 11, 4, and 102 cases were low, intermediate, and high, respectively, and 6.8% and 9.4% of cases were positive for IgM and IgG avidity tests, respectively (P=0.632). Agreement (Kappa value) between paired tests IgG-IgM, IgG-IgG avidity, and IgMIgG avidity was 0.080, 0.099, and 0.721, respectively (P<0.05). This study showed that conventional serologic tests (IgM and IgG levels) and IgG avidity correlate well each other and can be used to differentiate recent infections from old OT. It seems that reactivated old infections rather than recently acquired infections are majority of Iranian OT patients.

#Toxoplasma gondii #IgG #IgM #IgG avidity #ocular toxoplasmosis

참고문헌 (28)

참고문헌 신청

[학술지(정기간행물)] - Novais EA / 2014 / Patients with diffuse uveitis and inactive toxoplasmic retinitis lesions test PCR positive for Toxoplasma gondii in their vitreous and blood / Br J Ophthalmol 98 : 937 ~ 940

[학술지(정기간행물)] - Ali-Heydari S / 2013 / Diagnosis of antigenic markers of acute toxoplasmosis by IgG avidity immunoblotting / Parasite 20 : 18 ~

[학술지(정기간행물)] - Laboudi M / 2017 / Serodiagnosis of Toxoplasmosis: the effect of measurement of IgG avidity in pregnant women in Rabat in Morocco / Acta Trop 172 : 139 ~ 142

[학술지(정기간행물)] - Hill D / 2002 / Toxoplasma gondii: transmission, diagnosis and prevention / Clin Microbiol Infect 8 : 634 ~ 640

[학술지(정기간행물)] - Montoya JG / 2002 / Laboratory diagnosis of Toxoplasma gondii infection and toxoplasmosis / J Infect Dis 185 (Suppl) : 73 ~ 82

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!