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자료유형
학술저널
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대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제33권 제6호
발행연도
2019.1
수록면
500 - 505 (6page)

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초록· 키워드

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Purpose: To describe the clinical features of Korean patients with contact lens-induced limbal stem cell deficiency(CL-LSCD). Methods: Medical records of 22 patients who were diagnosed with CL-LSCD between 2014 and 2019 werereviewed retrospectively. Outcome measures included demographics, clinical presentation, treatment, clinicalcourse, and pattern of contact lens (CL) wear. Results: Forty-two eyes of 22 patients were found to have typical changes associated with CL-LSCD. Twenty(91%) patients were women and mean age was 36 ± 12 years. All patients had myopia with mean sphericalequivalent of -7.52 ± 3.2 diopter. Twenty (91%) patients had bilateral disease and the location of limbal involvementwas diffuse in 20 eyes (47.6%) and partial in 22 eyes (52.4%, superior in 20 eyes and inferior in 2 eyes). Fourteen (63.6%) patients complained of decreased visual acuity. Average period of CL wear was 14 ± 9years. Four patients used cosmetic colored CLs and four patients had a history of overnight CL wear. All 12patients who completed follow-up (28 ± 42 weeks) showed improvement in visual acuity and ocular surfacecondition after cessation of CL wear and medical treatment. Of them, five (42%) patients showed full recoverywhile seven (58%) showed partial recovery. Conclusions: If a patient with a history of CL wear for an extended period of time presents with decreased visualacuity, practitioners should perform detailed examinations with suspicion of CL-LSCD, including fluoresceinstaining. CL-LSCD is usually reversible and close follow-up with conservative treatment is recommended asthe initial treatment option.

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