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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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Sodium nitrite intoxication is a primary cause of severe methemoglobinemia, which may be fatal. In the past, nitrite-related deaths were rare, but cases of suicide with nitrite have been increasing in number in recent years. We analyzed 14 cases of fatal nitrite intoxication from January 2013 to February 2019. There was a different trend between the cases from the past and those from recent years. The former consisted of older individuals who ingested nitrite accidentally or intentionally, while the latter comprised younger individuals who used nitrite mostly for suicide. Most individuals showed dark purple or dark brown lividity and cherry-pink discoloration of the muscles. Postmortem methemoglobin levels, which were analyzed in 5 cases, were 30%-49%. Most nitrite and nitrate concentrations showed the highest concentration in the stomach contents, and it showed that the nitrite was converted into nitrate in the blood. To conclude, methemoglobin tests using a portable oximeter and quantitative tests of nitrite and nitrate, as well as a thorough investigation of the case and scene may help determine the cause of death.
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참고문헌 (8)
참고문헌 신청
YTN News / Two men who dies after drinking rice wine, poisoned with sodium nitrite
National Institute of Food and Drug Safety Evaluation / Sodium nitrite
이경원 / 2013 / 메트헤모글로빈혈증의 해독제: 메틸렌 블루 / 대한의사협회지 56(12):1084~1090
Chung NY / 2010 / Severe methemoglobinemia linked to gel-type topical benzocaine use: a case report / J Emerg Med 38:601~606
do Nascimento TS / 2008 / Methemoglobinemia: from diagnosis to treatment / Rev Bras Anestesiol 58:651~664
National Institute of Food and Drug Safety Evaluation / Sodium nitrite
이경원 / 2013 / 메트헤모글로빈혈증의 해독제: 메틸렌 블루 / 대한의사협회지 56(12):1084~1090
Chung NY / 2010 / Severe methemoglobinemia linked to gel-type topical benzocaine use: a case report / J Emerg Med 38:601~606
do Nascimento TS / 2008 / Methemoglobinemia: from diagnosis to treatment / Rev Bras Anestesiol 58:651~664
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