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Salivary Nitric Oxide, a Biomarker for Stress and Anxiety?
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논문 기본 정보

Type
Academic journal
Author
Journal
Korean Neuropsychiatric Association PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제13권 제3호 KCI Accredited Journals
Published
2016.1
Pages
311 - 315 (5page)

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Salivary Nitric Oxide, a Biomarker for Stress and Anxiety?
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Abstract· Keywords

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ObjectiveaaTo investigate if salivary nitrate correlates to the daily psychological stress and anxiety in a group of human subjects. MethodsaaThe convenient sample recruitment method was employed; data from seventy three subjects were analyzed. The Perceived Stress Scale (PSS) and Hamilton Anxiety Rating Scale (HAM-A) inventories were used to determine stress and anxiety scores respectively. Salivary nitric oxide was measured through nitrate (NOx) levels using the Griess reaction method. ResultsaaAlthough stress and anxiety were correlated. No significant correlation exists between salivary nitrate and daily psychological stress and anxiety in the study’s participants. ConclusionaaWhile all previous studies focused NOx levels in acute stress models. This is the first study to investigate the correlation between salivary nitrates and daily psychological stress and anxiety. Although stress and anxiety were correlated, there is no correlation between salivary nitrates and daily psychological stress and anxiety. Further studies are required to investigate this correlation using other biological samples such as plasma.
#Anxiety #Stress #Nitric oxide.

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References (24)

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Andrew PJ / 1999 / Enzymatic function of nitric oxide synthases / Cardiovasc Res 43:521~531 google schola Stuehr DJ / 1999 / Mammalian nitric oxide synthases / Biochim Biophys Acta 1411:217~230 google schola Amiri S / 2015 / Co-occurrence of anxiety and depressive-like behaviors following adolescent social isolation in male mice; possible role of nitrergic system / Physiol Behav 145:38~44 google schola Suzuki E / 2001 / Elevated plasma nitrate levels in depressive states / J Affect Disord 63:221~224 google schola McKnigh GM / 1999 / Dietary nitrate in man: friend or foe? / Br J Nutr 81:349~358 google schola

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