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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Previous studies have demonstrated that tenascin-N belongs to the family of tenascins, which are found in the extracellular matrix of various embryonic tissues, wounds, and tumors. Tenascin is expressed in the embryonic epithelium, including the neural epithelium from which neural crest cells emerge. However, the expression pattern and role of tenascin-N in the craniofacial region remains unknown. In this study, expression patterns of tenascin-N were confirmed in the mouse craniofacial region from embryonic day 12.5 (E12.5) to postnatal 11. In the diastema region, tenascin-N was strongly expressed in the mesenchyme from E12.5 to E14.5. Tenascin-N expression was also detected in the developing tooth germ. From the bell stage to the premature stage, tenascin- N was expressed in the odontoblasts and ameloblasts of the molar tooth germ, and the ameloblasts of the incisor tooth germ. These findings indicate that the spatial and temporal expression of tenascin-N might have a role in proper mouse craniofacial development, especially tooth development.
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참고문헌 (6)
참고문헌 신청
Hall BK / 2015 / Bones and Cartilage / Academic Press :281~298
Hall BK / 2015 / Bones and Cartilage / Academic Press :319~331
Richard P. Tucker / 2009 / The regulation of tenascin expression by tissue microenvironments / Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1793(5):888~892
John Neidhardt / 2003 / Tenascin-N: characterization of a novel member of the tenascin family that mediates neurite repulsion from hippocampal explants / Molecular and Cellular Neuroscience 23(2):193~209
Ting-Xin Jiang / 1992 / Mechanism of skin morphogenesis. I. Analyses with antibodies to adhesion molecules tenascin, N-CAM, and integrin / Developmental Biology 150(1):82~98
Hall BK / 2015 / Bones and Cartilage / Academic Press :319~331
Richard P. Tucker / 2009 / The regulation of tenascin expression by tissue microenvironments / Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1793(5):888~892
John Neidhardt / 2003 / Tenascin-N: characterization of a novel member of the tenascin family that mediates neurite repulsion from hippocampal explants / Molecular and Cellular Neuroscience 23(2):193~209
Ting-Xin Jiang / 1992 / Mechanism of skin morphogenesis. I. Analyses with antibodies to adhesion molecules tenascin, N-CAM, and integrin / Developmental Biology 150(1):82~98
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