지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 14 - 19 (6page)
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초록· 키워드
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Background: Gastroesophageal reflux disease is highly prevalent among overweight and obese individuals. This study aimed to investigate the effect of weight change on the development of erosive esophagitis (EE). Methods: A retrospective review of medical records from a university hospital in South Korea identified 7,123 subjects who underwent routine health checkups in 2012 and 2014. We excluded participants with EE in 2012. Body mass index (BMI) changes were classified as loss, stable, mild gain, or moderate gain. Results: Mild and moderate weight gain increased the odds of EE development (odds ratio [OR], 1.39; 95% confidence interval [CI], 1.06–1.84 and OR, 2.80; 95% CI, 1.87–4.21, respectively) relative to weight stability. Weight loss decreased the odds of EE development (OR, 0.58; 95% CI, 0.38–0.90) relative to weight stability. After stratifying subjects into three groups by baseline BMI, those with mild and moderate weight gain in the obese group and moderate gain in the overweight group showed increased odds of EE development relative to members of those groups whose weights remained stable (OR, 2.08; 95% CI, 1.29–3.36; OR, 3.92; 95% CI, 1.99–7.73 in obese group, and OR, 3.30; 95% CI, 1.64–6.64 in overweight group, respectively). In comparison, weight loss in the normal weight group decreased the odds of EE development relative to weight stability (OR, 0.38; 95% CI, 0.15–0.97). Conclusion: Weight gain was positively associated with EE development in overweight or obese individuals. Weight loss was negatively associated with EE development in normal-weight individuals.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Vakil N / 2006 / The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus / Am J Gastroenterol 101:1900~1920
Dent J / 2005 / Epidemiology of gastro-oesophageal reflux disease : a systematic review / Gut 54:710~717
El-Serag HB / 2014 / Update on the epidemiology of gastro-oesophageal reflux disease : a systematic review / Gut 63:871~880
Locke GR 3rd / 1997 / Prevalence and clinical spectrum of gastroesophageal reflux : a populationbased study in Olmsted County, Minnesota / Gastroenterology 112:1448~1456
Nilsson M / 2003 / Obesity and estrogen as risk factors for gastroesophageal reflux symptoms / JAMA 290:66~72
Dent J / 2005 / Epidemiology of gastro-oesophageal reflux disease : a systematic review / Gut 54:710~717
El-Serag HB / 2014 / Update on the epidemiology of gastro-oesophageal reflux disease : a systematic review / Gut 63:871~880
Locke GR 3rd / 1997 / Prevalence and clinical spectrum of gastroesophageal reflux : a populationbased study in Olmsted County, Minnesota / Gastroenterology 112:1448~1456
Nilsson M / 2003 / Obesity and estrogen as risk factors for gastroesophageal reflux symptoms / JAMA 290:66~72
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