지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.12
- 수록면
- 65 - 73 (9page)
이용수
초록· 키워드
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Background: The risk factors for renal cancer include smoking, obesity, hypertension, and exposure to trichloroethylene. Recent studies have shown that low sunlight exposure increases the risk of developing a range of cancers, including renal cancer. Given that most of the daytime is spent at work, a lack of occupational sunlight exposure can be a risk factor for renal cancer. Therefore, this study examined the relationship between occupational sunlight exposure and the incidence of renal cancer.
Methods: This was a university hospital-based case-control study on renal cancer. Of the 706 newly diagnosed patients with renal cell carcinoma (RCC), 633 cases were selected; 73 who had no occupational history were excluded. In addition, 633 controls were selected from the general population after 1:1 matching with respect to sex, age (within 5 years), and residential area (constituency-level). Information on sunlight exposure by the occupational group was referred to data from France. To estimate the association between occupational sunlight exposure and the RCC risk, the odds ratios (ORs) were calculated using conditional logistic regression analysis.
Results: Sunlight exposure was divided into quartiles and the risk of RCC was analyzed. The adjusted OR of RCC (OR: 0.664, 95% confidence interval: 0.449–0.983) was significantly lower for the Q4 group than Q1 group but the Q2 and Q3 groups did not show significant results. The risk of RCC tended to decrease with increasing exposure to sunlight (p for trend < 0.028).
Conclusions: Higher occupational sunlight exposure reduces the risk of RCC.
Methods: This was a university hospital-based case-control study on renal cancer. Of the 706 newly diagnosed patients with renal cell carcinoma (RCC), 633 cases were selected; 73 who had no occupational history were excluded. In addition, 633 controls were selected from the general population after 1:1 matching with respect to sex, age (within 5 years), and residential area (constituency-level). Information on sunlight exposure by the occupational group was referred to data from France. To estimate the association between occupational sunlight exposure and the RCC risk, the odds ratios (ORs) were calculated using conditional logistic regression analysis.
Results: Sunlight exposure was divided into quartiles and the risk of RCC was analyzed. The adjusted OR of RCC (OR: 0.664, 95% confidence interval: 0.449–0.983) was significantly lower for the Q4 group than Q1 group but the Q2 and Q3 groups did not show significant results. The risk of RCC tended to decrease with increasing exposure to sunlight (p for trend < 0.028).
Conclusions: Higher occupational sunlight exposure reduces the risk of RCC.
목차
ABSTRACT
BACKGROUND
METHODS
RESULTS
DISCUSSION
CONCLUSIONS
REFERENCES
참고문헌 (30)
참고문헌 신청
정규원 / 2017 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014 / Cancer Research and Treatment 49(2):292~305
Jemal A / 2008 / Cancer statistics, 2008 / CA Cancer J Clin 58(2):71~96
Dhôte R / 2000 / Risk factors for adult renal cell carcinoma: a systematic review and implications for prevention / BJU Int 86(1):20~27
Henschler D / 1995 / Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene / Arch Toxicol 69(5):291~299
Vamvakas S / 1998 / Renal cell cancer correlated with occupational exposure to trichloroethene / J Cancer Res Clin Oncol 124(7):374~382
Jemal A / 2008 / Cancer statistics, 2008 / CA Cancer J Clin 58(2):71~96
Dhôte R / 2000 / Risk factors for adult renal cell carcinoma: a systematic review and implications for prevention / BJU Int 86(1):20~27
Henschler D / 1995 / Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene / Arch Toxicol 69(5):291~299
Vamvakas S / 1998 / Renal cell cancer correlated with occupational exposure to trichloroethene / J Cancer Res Clin Oncol 124(7):374~382
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