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Recently, chitosan has increased attention in commercial applications in the food industry in terms of its biocompatibility and nontoxicity. In particular, chitosan has been used as a good hosting material for producing nanoparticles due to its unique property of ionic gelation. Chitosan has disadvantages such as low solubility at physiological pH, causing the metabolism of core material in the intestine and gastric juice. To overcome these limitations, various chitosan derivatives such as carboxylated, thiolated, and acylated chitosan have been studied. This review focuses on the changes in the physicochemical properties of chitosan nanoparticles with the introduction of hydrophobic groups, the application of functional nanocapsules as coatings, and their applicability in the food sector. The physicochemical modification of chitosan is expected to be an attractive research field for the development of chitosan applications for food as well as for improving bioavailability in functional food.
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참고문헌 (51)
참고문헌 신청
Ali A / 2018 / A review on chitosan and its nanocomposites in drug delivery / Int. J. Biol. Macromol. 109:273~286
Aranaz I / 2009 / Functional characterization of chitin and chitosan / Curr Chem Biol 3(2):203~230
Benech RO / 2002 / Inhibition of Listeria innocua in cheddar cheese by addition of nisin Z in liposomes or by in situ production in mixed culture / Appl. Environ. Microbiol 68(8):3683~3690
Bowman K / 2006 / Chitosan nanoparticles for oral drug and gene delivery / Int. J. Nanomed 1(2):117
Chen XG / 2003 / O/W emulsification for the selfaggregation and nanoparticle formation of linoleic acid modified chitosan in the aqueous system / J. Agric. Food. Chem 51(10):3135~3139
Aranaz I / 2009 / Functional characterization of chitin and chitosan / Curr Chem Biol 3(2):203~230
Benech RO / 2002 / Inhibition of Listeria innocua in cheddar cheese by addition of nisin Z in liposomes or by in situ production in mixed culture / Appl. Environ. Microbiol 68(8):3683~3690
Bowman K / 2006 / Chitosan nanoparticles for oral drug and gene delivery / Int. J. Nanomed 1(2):117
Chen XG / 2003 / O/W emulsification for the selfaggregation and nanoparticle formation of linoleic acid modified chitosan in the aqueous system / J. Agric. Food. Chem 51(10):3135~3139
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UCI(KEPA) : I410-ECN-0101-2020-594-000447275