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Objectives: Retro MTA is a fast setting Calcium silicate cement used in endodontic regeneration procedures in recent years. Beta-tricalcium phosphate (β-TCP) is another common biomaterial used for bone augmentation procedures. The present pilot study was undertaken to evaluate and compare the efficacy of Retro MTA and a mixture of Retro MTA / β-TCP for periodontal tissue regeneration. Materials and methods: In 4 beagle dogs, periodontal dehiscence type defects were created. In each side, one dehiscence defect was left empty as a control site and three treatment modalities were randomly applied for the others: Retro MTA covered with a collagen membrane, Retro MTA + β-TCP covered with a membrane and covering the defect with a membrane without any bone augmentation. After 8 weeks Animals were sacrificed and Histomorphometric and histologic analysis were conducted. Results: Histologic analysis showed more cementum formation for both Retro MTA+ β-TCP (3.74 ± 0.34 mm) and Retro MTA group (3.24 ± 0.56 mm) compared to control group 1 (1. 15 ± 0.45 mm) and control group 2 (0.78 ± 0.65 mm). Formation of newly formed bone and cementum in the experimental groups were significantly higher as compared to the control groups (P < 0.0001). Conclusions: Retro MTA or Retro MTA+ β-TCP covered with a collagen membrane resulted in regeneration of periodontal tissues. However, Retro MTA+ β-TCP showed tendency towards better results than the use of Retro MTA alone.
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참고문헌 (42)
참고문헌 신청
Kotsovilis S / 2010 / The adjunctive use of platelet-rich plasma in the therapy of periodontal intraosseous defects : a systematic review / J Periodontal Res 45(3):428~443
Gottlow J / 1984 / New attachment formation as the result of controlled tissue regeneration / J Clin Periodontol 11(8):494~503
Karring T / 1993 / Development of the biological concept of guided tissue regeneration—animal and human studies / Periodontol 1(1):26~35
Sculean A / 2005 / Formation of human cementum following different modalities of regenerative therapy / Clin Oral Investig 9(1):58~64
Lee S-J / 1993 / Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations / J Endod 19(11):541~544
Gottlow J / 1984 / New attachment formation as the result of controlled tissue regeneration / J Clin Periodontol 11(8):494~503
Karring T / 1993 / Development of the biological concept of guided tissue regeneration—animal and human studies / Periodontol 1(1):26~35
Sculean A / 2005 / Formation of human cementum following different modalities of regenerative therapy / Clin Oral Investig 9(1):58~64
Lee S-J / 1993 / Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations / J Endod 19(11):541~544
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