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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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Background: Scalp seborrheic dermatitis is a common disease characterized by flaking and itching of the scalp. Conventional treatment options, such as the use of topical corticosteroids and antifungal agents, may cause adverse effects and reduce user satisfaction rates; thus, it is important to explore other treatment options for scalp seborrheic dermatitis. Objective: We aimed to evaluate the efficacy and safety of a new-formula shampoo containing natural ingredients, including the extract of Rosa centifolia petals, epigallocatechin gallate, zinc pyrithione, and climbazole. Methods: A total of 50 patients with scalp seborrheic dermatitis were enrolled and divided into two groups: the new-formula shampoo-treated group and the 1.5% ciclopirox olamine shampoo-treated group. Clinical severity scores, sebum secretion, and inflammatory cytokines were assessed. In addition, patient satisfaction and adverse events were assessed using a questionnaire. Results: The new-formula shampoo was comparable with ciclopirox in reducing the clinical severity scores and sebum secretion. Patients' improvement scores and user satisfaction rates were higher in the new-formula shampoo group than in the 1.5% ciclopirox olamine shampoo-treated group. The inflammatory cytokine levels considerably changed in both groups during the course of the study. Conclusion: Thus, the new-formula shampoo can be considered a treatment option for patients with scalp seborrheic dermatitis.
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참고문헌 (28)
참고문헌 신청
Gupta AK / 2004 / Seborrheic dermatitis / J Eur Acad Dermatol Venereol 18:13~26
Dessinioti C / 2013 / Seborrheic dermatitis: etiology, risk factors, and treatments: facts and controversies / Clin Dermatol 31:343~351
김유리 / 2014 / Clinical Evaluation of a New-Formula Shampoo for Scalp Seborrheic Dermatitis Containing Extract of Rosa centifolia Petals and Epigallocatechin Gallate: A Randomized, Double-Blind, Controlled Study / Annals of Dermatology 26(6):733~738
Schwartz JR / 2013 / A comprehensive pathophysiology of dandruff and seborrheic dermatitis - towards a more precise definition of scalp health / Acta Derm Venereol 93:131~137
Gaitanis G / 2012 / The Malassezia genus in skin and systemic diseases / Clin Microbiol Rev 25:106~141
Dessinioti C / 2013 / Seborrheic dermatitis: etiology, risk factors, and treatments: facts and controversies / Clin Dermatol 31:343~351
김유리 / 2014 / Clinical Evaluation of a New-Formula Shampoo for Scalp Seborrheic Dermatitis Containing Extract of Rosa centifolia Petals and Epigallocatechin Gallate: A Randomized, Double-Blind, Controlled Study / Annals of Dermatology 26(6):733~738
Schwartz JR / 2013 / A comprehensive pathophysiology of dandruff and seborrheic dermatitis - towards a more precise definition of scalp health / Acta Derm Venereol 93:131~137
Gaitanis G / 2012 / The Malassezia genus in skin and systemic diseases / Clin Microbiol Rev 25:106~141
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