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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 130 - 141 (12page)
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초록· 키워드
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Background Escherichia coli and Klebsiella pneumoniae are two of the most common causes of urinary tract infection. The purpose of this study was to compare clinical characteristics and antimicrobial susceptibility of acute pyelonephritis (APN) between E. coli and K. pneumoniae. Materials and Methods We retrospectively reviewed medical records of patients with APN due to E. coli and K. pneumoniae between February 2014 and October 2017. Results A total 329 patients were enrolled; 258 cases of E. coli and 71 cases of K. pneumoniae. Among them, 219 cases were categorized into community-onset APN; 194 cases of E. coli and 25 cases of K. pneumoniae, and 110 patients were categorized into healthcare-associated APN; 64 cases of E. coli and 46 cases of K. pneumoniae. Catheter-associated APN was more frequently observed in K. pneumoniae in both community-onset and healthcare-associated APN. Neurogenic bladder, obstructive uropathy, urinary tract stone, bacteremia, and severe APN were more related to E. coli in healthcare-associated APN. In multivariate analysis, urinary catheter was more associated with K. pneumoniae (odds ratio [OR] 9.643, 95% confidence intervals [CI] 4.919-18.904, P = 0.001) and neurogenic bladder was more associated with E. coli (OR 3.765, 95% CI 1.112-12.772, P = 0.033). Extended-spectrum β-lactamase (ESBL) production was observed in 29.0% of E. coli in community-onset APN. Among ESBL, antimicrobial susceptibility of piperacillin/tazobactam was significantly higher in E. coli and ciprofloxacin was significantly higher in K. pneumoniae. Conclusion K. pneumoniae were more associated with urinary catheter while E. coli tended to be more associated with urogenital problems. ESBL positivity showed no significance in healthcare-associated APN. In community-onset APN, ESBL producing E. coli was more observed than K. pneumoniae.
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참고문헌 (34)
참고문헌 신청
Flores-Mireles AL / 2015 / Urinary tract infections: epidemiology, mechanisms of infection and treatment options / Nat Rev Microbiol 13:269~284
Magill SS / 2012 / Prevalence of healthcare-associated infections in acute care hospitals in Jacksonville, Florida / Infect Control Hosp Epidemiol 33:283~291
Ali S / 2018 / Healthcare associated infection and its risk factors among patients admitted to a tertiary hospital in Ethiopia : longitudinal study / Antimicrob Resist Infect Control 7:2
Allegranzi B / 2011 / Burden of endemic health-care-associated infection in developing countries : systematic review and meta-analysis / Lancet 377:228~241
Wagenlehner FM / 2012 / Epidemiology, treatment and prevention of healthcare-associated urinary tract infections / World J Urol 30:59~67
Magill SS / 2012 / Prevalence of healthcare-associated infections in acute care hospitals in Jacksonville, Florida / Infect Control Hosp Epidemiol 33:283~291
Ali S / 2018 / Healthcare associated infection and its risk factors among patients admitted to a tertiary hospital in Ethiopia : longitudinal study / Antimicrob Resist Infect Control 7:2
Allegranzi B / 2011 / Burden of endemic health-care-associated infection in developing countries : systematic review and meta-analysis / Lancet 377:228~241
Wagenlehner FM / 2012 / Epidemiology, treatment and prevention of healthcare-associated urinary tract infections / World J Urol 30:59~67
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