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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
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- 대한악안면성형재건외과학회 Maxillofacial Plastic Reconstructive Surgery Maxillofacial Plastic Reconstructive Surgery 제41권 제3호
- 발행연도
- 2019.1
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- 1 - 6 (6page)
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Background Botulinum toxin injection on the masticatory muscle induces the osteopenic condition on the ipsilateral condyle. Bisphosphonate suppresses bone resorption and is used to treat osteopenic or osteoporotic condition. This study aimed to evaluate the effect of bisphosphonate administration on prevention of condylar resorption and botulinum toxin A-induced disuse osteopenia in rats. Results The volume of the condyle and bone volume/tissue volume (BV/TV, %) showed a strong tendency towards statistical significance (p = 0.052 and 0.058). Trabecular thickness (Tb.Th, mm) and trabecular number (Tb.N, 1/mm) were significantly smaller in the Botox group than in the other groups (p < 0.05). The volume of the condyle and BV/TV in the bisphosphonate 100 and bisphosphonate 200 groups showed similar values when compared with the control group. Conclusion Bisphosphonate administration after botulinum toxin A injection in the masticatory muscles appears to prevent condyle resorption and botulinum toxin-induced disuse osteopenia in rats.
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참고문헌 (19)
참고문헌 신청
Matthys T / 2015 / Bone and cartilage changes in rabbit mandibular condyles after 1 injection of botulinum toxin / Am J Orthod Dentofac Orthop 148:999~1009
Davletov B / 2005 / Beyond BOTOX : advantages and limitations of individual botulinum neurotoxins / Trends Neurosci 28:446~452
Kim NH / 2010 / Botulinum toxin type A for the treatment of hypertrophy of the masseter muscle / Plast Reconstr Surg 125:1693~1705
Ernberg M / 2011 / Efficacy of botulinum toxin type A for treatment of persistent myofascial TMD pain : a randomized, controlled, double-blind multicenter study / Pain 152:1988~1996
Tsai CY / 2010 / Morphologic and bony structural changes in the mandible after a unilateral injection of botulinum neurotoxin in adult rats / J Oral Maxillofac Surg 68:1081~1087
Davletov B / 2005 / Beyond BOTOX : advantages and limitations of individual botulinum neurotoxins / Trends Neurosci 28:446~452
Kim NH / 2010 / Botulinum toxin type A for the treatment of hypertrophy of the masseter muscle / Plast Reconstr Surg 125:1693~1705
Ernberg M / 2011 / Efficacy of botulinum toxin type A for treatment of persistent myofascial TMD pain : a randomized, controlled, double-blind multicenter study / Pain 152:1988~1996
Tsai CY / 2010 / Morphologic and bony structural changes in the mandible after a unilateral injection of botulinum neurotoxin in adult rats / J Oral Maxillofac Surg 68:1081~1087
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