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Clinical Application of Botulinum Toxin to Contact Granuloma and Vocal Nodule : Clinical Application of Botulinum Toxin to Contact Granuloma and Vocal Nodule
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보툴리눔 독소를 이용한 성대육아종과 성대결절 치료

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Type
Academic journal
Author
Lee, Seung Won (순천향대학교 의과대학 이비인후-두경부외과학교실)
Journal
Korean Society of Larynegology, Phoniatrics and Logopedics 대한후두음성언어의학회지 대한후두음성언어의학회지 제30권 제2호
Published
2019.1
Pages
82 - 86 (5page)

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Clinical Application of Botulinum Toxin to Contact Granuloma and Vocal Nodule : Clinical Application of Botulinum Toxin to Contact Granuloma and Vocal Nodule
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In the field of otolaryngology-head and neck surgery, botulinum toxins are widely used for the treatment of spasmodic dysphonia and vocal tremors. Recently, the applications of botulinum toxin have gradually expanded with time, to include vocal fold granuloma, mutational falsetto, bilateral vocal cord paralysis, and chemical reduction for arytenoid dislocation as an adjunctive modality. According to a nation-wide multicenter study conducted by the Korean Society of Laryngology, Phoniatrics and Logopedics for treatment modality of contact granuloma, among the various treatment modalities, botulinum toxin injection showed the highest response rate and lowest recurrence rate in both primary and refractory cases. Therefore, botulinum toxin could be reserved as a second-line treatment for contact granuloma in which the first treatment was not effective, but also could be used as a first-line treatment depending on the patient's and institution's situation. For recalcitrant nodules, injection of botulinum toxin into the bilateral thyroarytenoid muscle will reduce glottal contact force and result in a forceful chemical voice rest. In special situations, botulinum toxin injection could be one of the alternative treatment options for recalcitrant vocal nodules.

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