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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.24 No.3
- 발행연도
- 2019.9
- 수록면
- 344 - 347 (4page)
- DOI
- 10.3746/pnf.2019.24.3.344
이용수
이 논문의 연구 히스토리 (2)
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초록· 키워드
오류제보하기
Pandanus fascicularis Lam has been shown to exert to a variety of physiological effects on edema, tumors, leprosy, spasm, inflammation, pain, and rheumatoid arthritis. In this study, the effects of a P. fascicularis extract on the production of lipopolysaccharide (LPS)-induced pro-inflammatory cytokines interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α expression and on the production of the inflammatory mediator, nitric oxide (NO), in RAW 264.7 cells were examined. The P. fascicularis extract decreased LPS-induced NO production. Moreover, enzyme-linked immunosorbent assays revealed that the P. fascicularis extract concentration-dependently suppressed LPS-induced production of the pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. These results suggest that the P. fascicularis extract has potential as an anti-inflammatory therapeutic substance for use in the prevention of the inflammatory disorder.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (19)
참고문헌 신청
Ahmed AU / 2011 / An overview of inflammation : mechanism and consequences / Front Biol 6:274
Boscá L / 2005 / Nitric oxide and cell viability in inflammatory cells : a role for NO in macrophage function and fate / Toxicology 208:249~258
Guha M / 2001 / LPS induction of gene expression in human monocytes / Cell Signal 13:85~94
Ham YM / 2017 / Litsenolide A2 : the major anti-inflammatory activity compound in Litsea japonica fruit / J Funct Foods 39:168~174
Kim KN / 2013 / Anti-inflammatory effects of trans-1,3-diphenyl-2,3-epoxypropane-1-one mediated by suppression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages / Food Chem Toxicol 53:371~375
Boscá L / 2005 / Nitric oxide and cell viability in inflammatory cells : a role for NO in macrophage function and fate / Toxicology 208:249~258
Guha M / 2001 / LPS induction of gene expression in human monocytes / Cell Signal 13:85~94
Ham YM / 2017 / Litsenolide A2 : the major anti-inflammatory activity compound in Litsea japonica fruit / J Funct Foods 39:168~174
Kim KN / 2013 / Anti-inflammatory effects of trans-1,3-diphenyl-2,3-epoxypropane-1-one mediated by suppression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages / Food Chem Toxicol 53:371~375
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