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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.24 No.3
- 발행연도
- 2019.9
- 수록면
- 327 - 337 (11page)
- DOI
- 10.3746/pnf.2019.24.3.327
이용수
초록· 키워드
오류제보하기
Sweet pepper is a non-pungent chili of the Capsicum annuum species and is an important ingredient in daily diets due to its characteristics such as pungency, aromas, and flavors. Sweet pepper is a rich source of bioactive compounds such as phenols, carotenoids, and flavonoids, which can promote potential health benefits against various non-communicable diseases. However, research focused on anti-Alzheimer’s disease (AD) properties of sweet peppers is limited. Thus, this study aimed investigate bioactive compounds (flavonoids, phenolic acids, and carotenoids), antioxidant activity and anti-AD properties of four colored sweet peppers (green, red, orange, and yellow) via their abilities to inhibit key enzymes relevant to AD [acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-secretase (BACE1)]. Extraction solvents [hexane, ethyl acetate, and 70% (v/v) aqueous ethanol] were also investigated. Results suggested that yellow sweet pepper have the highest content of flavonoids, while green sweet pepper have the highest contents of phenolic acids and red sweet peppers have the highest content of carotenoids. In terms of anti-AD properties, green sweet peppers exhibited the highest antioxidant, anti-BChE, and anti-BACE1 activities; however, yellow sweet pepper extract exhibited the highest amounts of AChE inhibition. Bioactive compounds in sweet red peppers may therefore have anti-AD properties, and may be useful for AD prevention.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (52)
참고문헌 신청
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Akbaraly NT / 2007 / Plasma carotenoid levels and cognitive performance in an elderly population : results of the EVA Study / J Gerontol A Biol Sci Med Sci 62:308~316
Al Othman ZA / 2011 / Determination of capsaicin and dihydrocapsaicin in Capsicum fruit samples using high performance liquid chromatography / Molecules 16:8919~8929
Anand P / 2013 / Flavonoids as lead compounds modulating the enzyme targets in Alzheimer’s disease / Med Chem Res 22:3061~3075
Asnin L / 2015 / Isolation and analysis of bioactive compounds in Capsicum peppers / Crit Rev Food Sci Nutr 55:254~289
Akbaraly NT / 2007 / Plasma carotenoid levels and cognitive performance in an elderly population : results of the EVA Study / J Gerontol A Biol Sci Med Sci 62:308~316
Al Othman ZA / 2011 / Determination of capsaicin and dihydrocapsaicin in Capsicum fruit samples using high performance liquid chromatography / Molecules 16:8919~8929
Anand P / 2013 / Flavonoids as lead compounds modulating the enzyme targets in Alzheimer’s disease / Med Chem Res 22:3061~3075
Asnin L / 2015 / Isolation and analysis of bioactive compounds in Capsicum peppers / Crit Rev Food Sci Nutr 55:254~289
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