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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.24 No.3
- 발행연도
- 2019.9
- 수록면
- 225 - 234 (10page)
- DOI
- 10.3746/pnf.2019.24.3.225
이용수
초록· 키워드
오류제보하기
Nanoemulsion drug delivery systems are advanced modes for delivering and improving the bioavailability of hydrophobic drugs and the drug which have high first pass metabolism. The nanoemulsion can be prepared by both high energy and low energy methods. High energy method includes high-pressure homogenization, microfluidization, and ultrasonication whereas low energy methods include the phase inversion emulsification method and the self-nanoemulsification method. Low energy methods should be preferred over high energy methods as these methods require less energy, so are more efficient and do not require any sophisticated instruments. However high energy methods are more favorable for food grade emulsion as they require lower quantities of surfactant than low energy methods. Techniques for formulation of nanoemulsion drug delivery system are overlapping in nature, especially in the case of low energy methods. In this review, we have classified different methods for formulation of nanoemulsion systems based on energy requirements, nature of phase inversion, and self-emulsification.
목차
ABSTRACT
INTRODUCTION
NANOEMULSION
FORMULATION TECHNIQUES OF NANOEMULSION DRUG DELIVERY SYSTEMS
ADVANTAGES OF NANOEMULSION DRUG DELIVERY SYSTEM
CONCLUSION
REFERENCES
참고문헌 (50)
참고문헌 신청
Acosta E / 2009 / Bioavailability of nanoparticles in nutrient and nutraceutical delivery / Curr Opin Colloid Interface Sci 14:3~15
Agrawal S / 2012 / A review on novel therapeutic strategies for the enhancement of solubility for hydrophobic drugs through lipid and surfactant based self micro emulsifying drug delivery system: a novel approach / Am J Drug Discovery Dev 2:143~183
Akbas E / 2018 / Formation of capsaicin loaded nanoemulsions with high pressure homogenization and ultrasonication / LWT 96:266~273
Alshamsan A / 2018 / Role of alternative lipid excipients in the design of self-nanoemulsifying formulations for fenofibrate: characterization, in vitro dispersion, digestion and ex vivo gut permeation studies / Front Pharmacol 9:1219
Armanet L / 2007 / Phase inversion of polyacrylamide-based inverse-emulsions: influence of inverting-surfactant type and concentration / J Appl Polym Sci 103:3567~3584
Agrawal S / 2012 / A review on novel therapeutic strategies for the enhancement of solubility for hydrophobic drugs through lipid and surfactant based self micro emulsifying drug delivery system: a novel approach / Am J Drug Discovery Dev 2:143~183
Akbas E / 2018 / Formation of capsaicin loaded nanoemulsions with high pressure homogenization and ultrasonication / LWT 96:266~273
Alshamsan A / 2018 / Role of alternative lipid excipients in the design of self-nanoemulsifying formulations for fenofibrate: characterization, in vitro dispersion, digestion and ex vivo gut permeation studies / Front Pharmacol 9:1219
Armanet L / 2007 / Phase inversion of polyacrylamide-based inverse-emulsions: influence of inverting-surfactant type and concentration / J Appl Polym Sci 103:3567~3584
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