지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Background: Candida albicans is a member of the normal flora of the skin, mucous membrane and gastrointestinal tract. Vaginal candidiasis remains a significant problem in women in childbearing age,Majority of the cases are caused by C. albicans and recurrence is common in spite of topical treatment.
Objective: The purpose of this study is to develop the antifungal agent from the medicinal herbs traditionally used in Korea.
Method: In this study, the extracts and essential oils from Foeniculum vulgare and Illicium verum were examined for antifungal activities against C. albicans.
Result: Dichloromethane extracts and essential oils from Foeniculum vulgare and Illicium verum showed antifungal activity against C. albicans. One fraction from Illicium verum with antifungal activity was founf out as 1-methoxy-4-(2-prophenyl) benzene.
Conclusion: Dichloromethane extract and 1-methoxy-4-(2-prophenyl) benzene with antifungal activity from Illicium verum could be the candidate for a new antifungal agent for candidiasis and other fungal diseases.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Adetumbi MA / 1983 / Allium sativum (garlic)-a natural antibiotic / Mdical Hypothesis 12 : 227 ~ 237
Barazani O / 1999 / Chemical variation among indigenous populations of Foeniculum vulgare var. vulgare in Israel. / Planta Med 6 : 486 ~ 489
Bennet ML / 1999 / General pustular eruption associated with oral terbinaine / Int J Dermatol 38 : 596 ~ 600
Chang K / 2001 / Fumignant activity of (E)-anithole identified in Illicium verum fruit against Blattella gemanica / Pest Manag Sci 58 : 161 ~ 166
Cox PA / 1994 / The ethnobotanical approach to drug discovery :Strengths and limitations in Ethnobotant and the search for new drugs / Chichster (Ciba Foundation Symposium 185) : 2
Barazani O / 1999 / Chemical variation among indigenous populations of Foeniculum vulgare var. vulgare in Israel. / Planta Med 6 : 486 ~ 489
Bennet ML / 1999 / General pustular eruption associated with oral terbinaine / Int J Dermatol 38 : 596 ~ 600
Chang K / 2001 / Fumignant activity of (E)-anithole identified in Illicium verum fruit against Blattella gemanica / Pest Manag Sci 58 : 161 ~ 166
Cox PA / 1994 / The ethnobotanical approach to drug discovery :Strengths and limitations in Ethnobotant and the search for new drugs / Chichster (Ciba Foundation Symposium 185) : 2
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