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Objective: Dyslipidemia is recognized as a prominent risk factor for cardiovascular and cerebrovascular diseases but it ismanageable through therapeutic and lifestyle intervention. Interpreting the latest guidelines is essential for an application ofrecommendation from guidelines into clinical practice. Therefore, this study aimed to compare the most recent guidelines ondyslipidemia treatment recommendations in Korea and USA. Methods: This study analyzed and compared 2015 Korean guidelinesfor the management of dyslipidemia, 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline and2016 supportive guidelines from ACC. Results: A comparison was made focused on the following: target patients based oncardiovascular risk assessment, target goal, and treatment strategies including statin and non-statin therapies. Four target patientgroups by risk were suggested in 2015 Korean guideline and cardiovascular risk factors were also considered for initiation of lipidlowering therapy. Titrated statin regimen was recommended by Korean guideline to reach LDL cholesterol and non-HDLcholesterol target level. In 2013 ACC/AHA guideline, four statin benefit group was introduced considering ASCVD risk and highintensity statin or intermediate intensity statin use were recommended without dose titration. 2016 update was to support nonstatintherapy based on updated evidence and new consideration of ezetimibe, PCSK9-inhibitor and bile acid sequestrant wasbrought up. Conclusion: Guidelines are continuously updating as new and important clinical data are constantly released alongwith the advent of newly approved drugs for lipid disorder. This article provides resources that facilitates uptake of theserecommendations into clinical practice.
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참고문헌 (18)
참고문헌 신청
AIM-HIGH Investigators / 2011 / Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy / N Engl J Med 365 : 2255 ~ 2267
Benjamin EJ / 2017 / Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association / Circulation 135 (10) : e146 ~ e603
Cannon CP / 2015 / Ezetimibe added to statin therapy after acute coronary syndromes / N Engl J Med 372 : 2387 ~ 2397
Carreras ET / 2017 / Dyslipidemia : Current Therapies and Guidelines for Treatment / US Cardiology Review 11 (1) : 10 ~ 15
Committee for the Korean Guidelines for the Management of Dyslipidemia / 2016 / 2015 Korean Guidelines for the Management of Dyslipidemia: Executive Summary (English Translat
Benjamin EJ / 2017 / Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association / Circulation 135 (10) : e146 ~ e603
Cannon CP / 2015 / Ezetimibe added to statin therapy after acute coronary syndromes / N Engl J Med 372 : 2387 ~ 2397
Carreras ET / 2017 / Dyslipidemia : Current Therapies and Guidelines for Treatment / US Cardiology Review 11 (1) : 10 ~ 15
Committee for the Korean Guidelines for the Management of Dyslipidemia / 2016 / 2015 Korean Guidelines for the Management of Dyslipidemia: Executive Summary (English Translat
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