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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국전문물리치료학회 한국전문물리치료학회지 한국전문물리치료학회지 제15권 제4호
발행연도
2008.1
수록면
50 - 58 (9page)

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초록· 키워드

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The purpose of this study was to investigate the effects of the task-oriented training according to the application time with the change of motor and cognition function. Focal ischemic brain injury was produced in Sprague-Dawley rats (20 rats, 250±50 g) through middle cerebral artery occlusion (MCAo). Before MCAo induction, all rats were trained in treadmill training and Morris water maze training for 1 week. Then they were randomly divided into groups; Group Ⅰ: MCAo induction (n1=5), Group Ⅱ: the application for simple treadmill task training after MCAo induction (n2=5), Group Ⅲ: the application for Morris water maze cognitive task training after MCAo induction (n3=5), Group Ⅳ: the application for progressive treadmill task training and Morris water maze cognitive task training after MCAo induction (n4=5). Modified limb placing tests (MLPTs) and motor tests (MTs) were performed to test motor function and then Morris water maze acquisition test (MWMAT) and Morris water maze retention test (MWMRT) were performed to test cognitive function. For MTs, there were significant interactions among the groups with the time (p<.001). Group Ⅳ showed the steeper increasing pattern than those in other Groups on the 7th and 14th day. For MLPTs, there were significant interactions among the groups with the time (p<.001). The scores in Group Ⅲ, Ⅳ had showed the more decreasing pattern than those in Group Ⅰ, Ⅱ since the 7th day and 14th day. For MWMAT, there were significant interactions among the groups with the time (p<.001). Group Ⅱ found the quadrant circular platform showed the steeper decreasing pattern than that in Group Ⅰ on the 9th, 10th, 11th and 12th day. Group Ⅲ, Ⅳ found the quadrant circular platform showed the slower decreasing pattern than that in Group Ⅰ, Ⅱ. For MWMRT, there were significant differences among the four groups (p<.001). The time to dwell on quadrant circular platform in Group Ⅳ on the 13th day was the longest compared with other groups. These results suggested that the combined task training was very effective to improve the motor and cognition function for the rats affected on their focal ischemic brain injury.

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