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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 44 - 52 (9page)
이용수
초록· 키워드
오류제보하기
It is known that individual factors as cognitive, perception, emotion, and motivation may greatly influence on recovery from neurologic region. This study was to investigate the effects of environmental reinforcement through motivation to perform the tasks voluntarily on motor and cognition function in rats with focal ischemic brain injury. Focal ischemic brain injury was induced in Sprague-Dawley rats (15 rats, 250±50 g) through middle cerebral artery occlusion (MCAo). And then, experiment groups were randomly divided into three groups; The control group: MCAo induction (n1=5), the environmental reinforcement (ER) group: the application for ER after MCAo induction (n2=5), the environmental reinforcement through motivation (ERM) group: the application for ERM after MCAo induction (n3=5). The climbing test (CT) and the modified limb placing tests (MLPTs) to measure the motor function and the Morris water maze acquisition test (MWMAT) and the Morris water maze retention test (MWMRT) to measure the cognitive function were performed. For the CT, the ERM group was significantly larger than the ER group. For the MLPTs, the ERM group was significantly decreased compared to other groups. For the MWMAT, the time to find the circular platform in the ERM group significantly decreased compared to other groups. For the MWMRT, the time to dwell on the quadrant circular platform in the ERM group was significantly increased compared to other groups. These results suggested that the ERM could improve the motor and cognitive functions in the rats with focal ischemic brain injury.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Bederson JB / 1986 / Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination / Stroke 17 (3) : 472 ~ 476
Belayev A / 2003 / Enriched environment delays the onset of hippocampal damage after global cerebral ischemia in rats / Brain Res 964 (1) : 121 ~ 127
Biernaskie J / 2001 / Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury / J Neurosci 21 (14
Briones TL / 2004 / Stability of synaptic plasticity in the adult rat visual cortex induced by complex environment exposure / Brain Res 1018 (1) : 130 ~ 135
Dahlqvist P / 2004 / Environmental enrichment reverses learning impairment in the Morris water maze after focal cerebral ischemia in rats / Eur J Neurosci 19 (8) : 2288 ~ 229
Belayev A / 2003 / Enriched environment delays the onset of hippocampal damage after global cerebral ischemia in rats / Brain Res 964 (1) : 121 ~ 127
Biernaskie J / 2001 / Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury / J Neurosci 21 (14
Briones TL / 2004 / Stability of synaptic plasticity in the adult rat visual cortex induced by complex environment exposure / Brain Res 1018 (1) : 130 ~ 135
Dahlqvist P / 2004 / Environmental enrichment reverses learning impairment in the Morris water maze after focal cerebral ischemia in rats / Eur J Neurosci 19 (8) : 2288 ~ 229
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