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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives: Effective genetic toxicology and molecular biology research techniques and strategies that are highly correlated with the carcinogenic inhalation toxicity test and related research are required. The aim of this study was to maximize the utilization of chemical substances to prevent workers’ occupational diseases. Methods: We surveyed the literature, domestic and international references, and the status of relevant domestic and foreign professional organizations. Expert advisory opinions were reflected, and experts were consulted by participating in domestic and overseas academic conferences. Results: The current status of domestic and international genotoxic toxicity evaluation was examined through various documents from related organizations. Cell models for in vitro lung toxicology were investigated and summarized, and the human resourcesand performance results of genetic toxicity studies and pilot projects were compared and analyzed by holding an advisory meeting. We examined domestic and international genotoxicity guidelines and investigatednew test methods for the development of genotoxicity and carcinogenicity. Ultimately, we described long-term future predictions, including the implementation of our researchers’ recommendations and occupational genetic toxicology forecasts for future worker health protection. Conclusions: This research project aims to establish current genetic toxicology and molecular biology research techniques and strategies that can maximize the linkage with the carcinogenic inhalation toxicity test and research in the future. We expanded the study of genetic toxicity and establish afoundation forgenetic toxicity in accordance with research trends in Korea and abroad.
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참고문헌 (33)
참고문헌 신청
Seo Y / 2007 / Study on the establishment of evaluation system for genotoxicity using genotoxic biomarker genes
David Kirkland / 2005 / Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens / Mutation Research/Genetic Toxicology and Environmental Mutagenesis 584(1-2):1~256
Sohn SJ / 2015 / A study on the introduction of internationally adopted genotoxicity testing battery and guidelines for pharmaceuticals
Seo JW / 2016 / Development of Safety Pharmacology method using 3D cardiac tissue model with Human iPS-induced cardiomyocyte
김정곤 / 2013 / OECD QSAR Application Toolbox를 이용한 화학물질의 건강유해성 및 생태독성 예측 / 한국환경보건학회지 39(2):130~137
David Kirkland / 2005 / Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens / Mutation Research/Genetic Toxicology and Environmental Mutagenesis 584(1-2):1~256
Sohn SJ / 2015 / A study on the introduction of internationally adopted genotoxicity testing battery and guidelines for pharmaceuticals
Seo JW / 2016 / Development of Safety Pharmacology method using 3D cardiac tissue model with Human iPS-induced cardiomyocyte
김정곤 / 2013 / OECD QSAR Application Toolbox를 이용한 화학물질의 건강유해성 및 생태독성 예측 / 한국환경보건학회지 39(2):130~137
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