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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 957 - 963 (7page)
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초록· 키워드
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Deoduk (Codonopsis lanceolata) has a complex chemical composition that includes polyphenols, saponins, amino acids, and other unidentified compounds. The contents of tangshenoside and lobetyolin are considered as standard of quality evaluation of Deoduk. In this study, an ultra-performance liquid chromatography (UPLC) method was developed for the quantitative determination of the two marker constituents, tangshenoside and lobetyolin. The methods for determining the standards of quality were validated by measuring their linearity, specificity, limit of detection (LOD), limit of quantification (LOQ), precision, and accuracy using UPLC. Reversed-phase UPLC analysis was conducted quantitatively to identify individual tangshenoside and lobetyolin in Deoduk extracted with 50% (v/v) aqueous ethanol. We used 21 samples to carry out quantitative analysis of tangshenoside and lobetyolin. Based on their dry weights, the levels of tangshenoside and lobetyolin were 0.36~3.54 mg/g, 0.24~1.29 mg/g, respectively. These results will be valuable as basic data for standardization of Korean Deoduk.
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참고문헌 (32)
참고문헌 신청
Cha A / 2012 / Antilipogenic and anti-inflammatory activities of Codonopsis lanceolata in mice hepatic tissues after chronic ethanol feeding / J Biomed Biotechnol 2012:141395
Gao SM / 2018 / Traditional uses, phytochemistry, pharmacology and toxicology of Codonopsis: A review / J Ethnopharmacol 219:50~70
He X / 2015 / Chemical fingerprint analysis for quality control and identification of Ziyang green tea by HPLC / Food Chem 171:405~411
Hossen MJ / 2016 / Codonopsis lanceolata:A review of its therapeutic potentials / Phytother Res 30:347~356
Ichikawa M / 2009 / Simultaneous determination of seven saponins in the roots of Codonopsis lanceolata by liquid chromatography-mass spectrometry / J Nat Med 63:52~57
Gao SM / 2018 / Traditional uses, phytochemistry, pharmacology and toxicology of Codonopsis: A review / J Ethnopharmacol 219:50~70
He X / 2015 / Chemical fingerprint analysis for quality control and identification of Ziyang green tea by HPLC / Food Chem 171:405~411
Hossen MJ / 2016 / Codonopsis lanceolata:A review of its therapeutic potentials / Phytother Res 30:347~356
Ichikawa M / 2009 / Simultaneous determination of seven saponins in the roots of Codonopsis lanceolata by liquid chromatography-mass spectrometry / J Nat Med 63:52~57
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