메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한통증학회 The Korean Journal of Pain The Korean Journal of Pain 제17권 제2호
발행연도
2004.1
수록면
3 - 3 (1page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background: The purpose of this study was to characterize an animal model of persistent mechanical hyperalgesia induced by repeated intraplantar injection of low pH saline. Methods: Saline, at pHs of 4, 5, 7 and 7.4, was intraplantarily injected into the hind paw twice, 5 days apart. To quantify the hyperalgesia, the withdrawal threshold (WT) to mechanical stimuli was measured on the following schedule: before the first injection; 2 h and 4 h after the first injection; before the second injection and 4 h and weekly (6 weeks) after the second injection. The paw withdrawal latency to radiant heat was also measured with pH 4 saline. Mechanical hyperalgesia (MH) due to an intraplantar, subcutaneous injection was compared with that of a gastrocnemius muscle injection at pH 4. Results: Two unilateral injections of pH 4 and 5 saline solutions caused bilateral mechanical, but not heat hyperalgesia, which lasted 3-4 weeks. An intraplantar injection of pH 4 saline showed a higher WT than the gastrocnemius muscle injection 4 hours after the second injection, but there was no significant difference between the two. Conclusions: Repeated intraplantar injections of low pH saline produced bilateral long-lasting MH in rats, but there was no significant difference in the WT between muscle and subcutaneous injections.

목차

등록된 정보가 없습니다.

참고문헌 (28)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0