아스피린과민성 천식 환자에게 발생한 클로르페니라민 알레르기

이승호; 정희석; 윤태영; 장은주; 김경숙; 김미경

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자료유형: 학술저널

저자정보: 이승호 정희석 윤태영 장은주 김경숙 김미경

저널정보: 대한천식알레르기학회(구 대한알레르기학회) 천식 및 알레르기 천식 및 알레르기 제30권 제1호

발행연도: 2010.1

수록면: 55 - 58 (4page)

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Antihistamine is one of the most widely used medications for allergic rhinitis, urticaria and other allergic conditions. However, the prevalence of adverse skin reactions induced by antihistamines are quite low because they can mask the skin lesions. A 43-year-old man experienced generalized urticaria, angioedema, wheezing, dyspnea and hypotension after taking Minoltrochy composed of cetylpyridium and chlorpheniramine for common cold. Skin prick tests with the extracts of cetylpyridium and chlorpheniramine showed a weak positive reaction to chlorpheniramine. Oral challenge tests showed a positive reaction to chlorpheniramine but not to cetylpyridium. Aspirin-intolerant asthma was confirmed by the aspirin oral challenge test. With these results, we confirmed the case of drug allergy to chlorpheniramine in a patient with aspirin-intolerant asthma.

#Allergic reaction #Chlorpheniramine #Aspirin

참고문헌 (17)

참고문헌 신청

Asero R / 2001 / Multiple drug allergy syndrome: a distinct clinical entity : 18 ~ 22

Assouere MN / 2002 / Cutaneous drug eruption with two antihistamine drugs of a same chemical family: cetirizine and hydroxyzine / Ann Dermatol Venereol 129 : 1295 ~ 8

Brown VL / 2005 / Cutaneous adverse reaction to oral chlorpheniramine detected with patch testing / Contact Dermatitis 52 : 49 ~ 50

Cusano F / 1989 / Errico G. Contact dermatitis from dexchlorpheniramine / Contact Dermatitis 21 : 340 ~

Inomata N / 2009 / Multiple H1-antihistamine- induced urticaria / J Dermatol 36 : 224 ~ 7

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주요연구분야 의약학 > 임상의학 > 내과학

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