지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 7 - 13 (7page)
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초록· 키워드
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Purpose: To identify the risk factors associated with fluoroquinolone resistance in patients undergoing cataract surgery.
Methods: A total of 1,125 patients (1,125 eyes) who underwent cataract surgery at Veterans Health Service Medical Center from May 2011 to July 2012 were enrolled in this study. Conjunctival cultures were obtained from the patients on the day of surgery before instillation of any ophthalmic solutions. The medical records of patients with positive coagulase negative staphylococcus (CNS) and Staphylococcus aureus (S. aureus) cultures were reviewed to determine factors associated with fluoroquinolone resistance.
Results: Of 734 CNS and S. aureus cultures, 175 (23.8%) were resistant to ciprofloxacin, levofloxacin, gatifloxacin, or moxifloxacin. Use of fluoroquinolone within 3 months and within 1 year before surgery, topical antibiotic use other than fluoroquinolone, systemic antibiotic use, recent hospitalization, ocular surgery, intravitreal injection and use of eyedrops containing benzalkonium chloride were significantly more frequent in resistant isolates than in susceptible isolates. In multivariable logistic regression analysis, ocular surgery (odds ratio [OR], 8.457), recent hospitalization (OR, 6.646) and use of fluoroquinolone within 3 months before surgery (OR, 4.918) were significant predictors of fluoroquinolone resistance, along with intravitreal injection (OR, 2.976), systemic antibiotic use (OR, 2.665), use of eyedrops containing benzalkonium chloride (OR, 2.323), use of fluoroquinolone within 1 year before surgery (OR, 1.943) and topical antibiotic use other than fluoroquinolone (OR, 1.673).
Conclusions: Recent topical fluoroquinolone use, hospitalization and ocular surgery were significantly associated with fluoroquinolone resistance in CNS and S. aureus isolates from ocular culture.
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참고문헌 (22)
참고문헌 신청
Alabiad CR / 2011 / Antimicrobial resistance profiles of ocular and nasal flora in patients undergoing intravitreal injections / Am J Ophthalmol 152 : 999 ~ 1004
Asbell PA / 2008 / Ocular TRUST: nationwide antimicrobial susceptibility patterns in ocular isolates / Am J Ophthalmol 145 : 951 ~ 958
Barberis-Maino L / 1987 / IS431, a staphylococcal insertion sequence-like element related to IS26 from Proteus vulgaris / Gene 59 : 107 ~ 113
Chang DF / 2007 / Prophylaxis of postoperative endophthalmitis after cataract surgery: results of the 2007 ASCRS member survey / J Cataract Refract Surg 33 : 1801 ~ 1805
Chenia HY / 2006 / Analysis of the mechanisms of fluoroquinolone resistance in urinary tract pathogens / J Antimicrob Chemother 58 : 1274 ~ 1278
Asbell PA / 2008 / Ocular TRUST: nationwide antimicrobial susceptibility patterns in ocular isolates / Am J Ophthalmol 145 : 951 ~ 958
Barberis-Maino L / 1987 / IS431, a staphylococcal insertion sequence-like element related to IS26 from Proteus vulgaris / Gene 59 : 107 ~ 113
Chang DF / 2007 / Prophylaxis of postoperative endophthalmitis after cataract surgery: results of the 2007 ASCRS member survey / J Cataract Refract Surg 33 : 1801 ~ 1805
Chenia HY / 2006 / Analysis of the mechanisms of fluoroquinolone resistance in urinary tract pathogens / J Antimicrob Chemother 58 : 1274 ~ 1278
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