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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 157 - 161 (5page)
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초록· 키워드
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Objective The purpose of present study was to evaluate association between neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) and endometrial hyperplasia (EH).
Methods One hundred and ten women with abnormal uterine bleeding were included into the study. Blood samples were drawn from all patients to obtain complete blood cell counts, neutrophil-leukocyte ratio and platelet-leukocyte ratio before endometrial curettage procedure initiated. The patients were divided into three groups due to their pathological results: group 1, patients with EH without atypia (n=40); group 2, patients with EH with atypia (n=15); and group 3, patients with neither hyperplasia nor cancer as control group (n=55). Blood cell counts, NLRs and PLRs were compared among these groups.
Results Based on hemoglobin and platelet counts, there was no significant difference among these groups (P>0.05). Leukocyte and neutrophil counts were higher in group 2 (EH with atypia) than group 1 and group 3 (P<0.01). NLR of group 2 was significantly elevated when compared to group 1 and group 3 (P=0.004). PLR was higher in group 1 and group 2 than control group (P=0.024).
Conclusion Non-specific inflammatory markers such as NLR and PLR were elevated in women with atypical EH. These markers may be used as a predictor of atypical EH in patients with abnormal uterine bleeding.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Acmaz G. / 2014 / Are neutrophil/lymphocyte and platelet/lymphocyte ratios associated with endometrial precancerous and cancerous lesions in patients with abnormal uterine bl
Akhmedkhanov A. / 2001 / Role of exogenous and endogenous hormones in endometrial cancer : review of the evidence and research perspectives / Ann N Y Acad Sci 943 : 296 ~ 315
Austin H. / 1991 / Endometr
Ayhan A. / 2006 / The value of preoperative platelet count in the prediction of cervical involvement and poor prognostic variables in patients with endometrial carcinoma / G
Calle EE. / 2004 / Overweight, obesity and cancer : epidemiological evidence and proposed mechanisms / Nat Rev Cancer 4 : 579 ~ 591
Akhmedkhanov A. / 2001 / Role of exogenous and endogenous hormones in endometrial cancer : review of the evidence and research perspectives / Ann N Y Acad Sci 943 : 296 ~ 315
Austin H. / 1991 / Endometr
Ayhan A. / 2006 / The value of preoperative platelet count in the prediction of cervical involvement and poor prognostic variables in patients with endometrial carcinoma / G
Calle EE. / 2004 / Overweight, obesity and cancer : epidemiological evidence and proposed mechanisms / Nat Rev Cancer 4 : 579 ~ 591
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