Could the Platelet-to-Lymphocyte Ratio be a Novel Marker for Predicting Invasiveness of Cervical Pathologies?

Kose, Mesut; Celik, Fatih; Kose, Seda Kayman; Arioz, Dagistan Tolga; Yilmazer, Mehmet

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저자정보: Kose, Mesut (Department of Obstetrics and Gynecology, Faculty of Medicine, Afyonkarahisar Kocatepe University) Celik, Fatih (Department of Obstetrics and Gynecology, Faculty of Medicine, Afyonkarahisar Kocatepe University) Kose, Seda Kayman (Department of Obstetrics and Gynecology, Faculty of Medicine, Afyonkarahisar Kocatepe University) Arioz, Dagistan Tolga (Department of Obstetrics and Gynecology, Faculty of Medicine, Afyonkarahisar Kocatepe University) Yilmazer, Mehmet (Department of Obstetrics and Gynecology, Faculty of Medicine, Afyonkarahisar Kocatepe University)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제3호

발행연도: 2015.1

수록면: 923 - 926 (4page)

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Purpose: To determine whether the preoperative platelet to lymphocyte ratio (PLR) could predict invasiveness of cervical pathologies. Materials and Methods: Patients with preinvasive and invasive diseases were reviewed retrospectively, over a nine-year period, 2005-2014. The pathological records and completed blood counts of the patients were collected and recorded in the SPSS program. Patients were divided in two groups, preinvasive and invasive. Results: The median PLR was significantly higher in the invasive group than in the preinvasive group (p=0.03). There was a correlation between invasion of cervical cancer and white blood cell count, red cell distributing width (RDW), neutrophil-lymphocyte ratio (NLR), and PLR. Conclusions: This study showed that patients with uterine cervical cancer may present with leukocytosis, increased RDW, NLR and PLR. These cheap and easily available parameters, especially PLR, may provide useful information about the invasiveness of cervical lesions.

#Platelet to lymphocyte ratio #cervical pathologies #invasive #preinvasive

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Kose, Mesut

소속기관 Department of Obstetrics and Gynecology, Faculty of Medicine, Afyonkarahisar Kocatepe University