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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 527 - 534 (8page)
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Objective: To investigate the safety of umbilical cord milking on both the mother and neonate among very preterm deliveries of less than 33 weeks of gestation.
Methods: Pregnant women who were expected to deliver at between 24 0/7 and 32 6/7 weeks of gestation were randomized to either the umbilical cord milking or immediate cord clamping group. Maternal and neonatal data associated with delivery, in addition to neonatal morbidity and mortality data, were collected and analyzed.
Results: Of the 66 preterm deliveries included in the study, 34 were randomized into the milking and 32 into the clamping group. Differences between maternal pre- and post-partum hemoglobin levels were 1.35 g/dL in the milking and 1.58 g/dL in the clamping group (P=0.451). Neonatal Apgar scores at both 1 and 5 minutes, initial blood gas analysis results, body temperature at admission, need for early intubation, and maximum bilirubin levels were all similar between the 2 groups. However, neonatal hemoglobin levels at birth (15.79 vs. 14.69 g/dL; P<0.05) and at 24 hours of age (14.83 vs. 13.29 g/dL; P<0.05) were significantly higher in the milking group. Neonates in the clamping group required more blood transfusion (1.78 vs. 0.93; P=0.049), and a higher percentage of neonates in the clamping group required inotropic drugs (63% vs. 29%; P=0.007). The mortality rate was significantly lower in the milking group (6% vs. 28%; P=0.015).
Conclusion: Umbilical cord milking can be a safe and beneficial procedure for both the mother and the neonate in deliveries of less than 33 weeks of gestation.
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참고문헌 (21)
참고문헌 신청
Backes CH / 2014 / Placental transfusion strategies in very preterm neonates: a systematic review and metaanalysis / Obstet Gynecol 124 : 47 ~ 56
Committee on Obstetric Practice / 2012 / American College of Obstetricians and Gynecologists. Committee opinion no.543: timing of umbilical cord clamping after birth / Obstet
Dang D / 2015 / Umbilical cord milking reduces need for red cell transfusions and improves neonatal adaptation in preterm infants: metaanalysis / J Obstet Gynaecol Res 41 :
Evans N / 2006 / Assessment and support of the preterm circulation / Early Hum Dev 82 : 803 ~ 810
Ghavam S / 2014 / Effects of placental transfusion in extremely low birthweight infants: meta-analysis of long- and short-term outcomes / Transfusion 54 : 1192 ~ 1198
Committee on Obstetric Practice / 2012 / American College of Obstetricians and Gynecologists. Committee opinion no.543: timing of umbilical cord clamping after birth / Obstet
Dang D / 2015 / Umbilical cord milking reduces need for red cell transfusions and improves neonatal adaptation in preterm infants: metaanalysis / J Obstet Gynaecol Res 41 :
Evans N / 2006 / Assessment and support of the preterm circulation / Early Hum Dev 82 : 803 ~ 810
Ghavam S / 2014 / Effects of placental transfusion in extremely low birthweight infants: meta-analysis of long- and short-term outcomes / Transfusion 54 : 1192 ~ 1198
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