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자료유형
학술저널
저자정보
Jinjoo Kim (Kyung Hee University) 이나미 (중앙대학교) 이대용 (중앙대학교) 정성훈 (경희대학교) Yong Sung Choi (Kyung Hee University)
저널정보
대한주산의학회 Perinatology Perinatology Vol.31 No.1
발행연도
2020.1
수록면
26 - 31 (6page)

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Objective: Milk delivered to human milk banks should be pasteurized and stored at -20°C in order to inactivate any microbial agents that may be present. We aimed to quantify the changes in the macronutrient composition of donor human milk (DHM) that underwent Holder pasteurization (HoP) and subsequent storage. Methods: A total of 54 breast milk samples from 26 healthy lactating mothers were collected at different time points after delivery, at intervals ranging from 1-6 months. We measured the carbohydrate, protein, fat, and energy content before and after HoP. After HoP, DHM was stored at -20°C, and the nutrients were measured at 1, 2, 4, 8, 12, 16, and 20 weeks after storage commenced. Results: The difference in time between expression of milk and pasteurization did not affect the concentration of macronutrients. However, the protein, fat, and energy contents decreased significantly during HoP. The mean values of the protein, fat, and energy contents in DHM pre-HoP were 1.2 g/dL, 3.7 g/dL, and 72.1 kcal/dL, compared with post-HoP values of 1.0 g/dL, 3.1 g/dL, and 65.2 kcal/dL, respectively. Although HoP reduced the protein, fat, and energy contents of donor milk by 16.7%, 16.2%, and 9.6%, respectively, the carbohydrate content was not reduced. Moreover, there was a significant decrease in the content of all the analyzed macronutrients following storage for up to 20 weeks. Conclusion: The post-HoP storage period affected nutrients, with several human milk components decreasing in content after HoP. As such, DHM after HoP may need fortification to ensure normal infant growth.

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